Alzheimer's & dementia : the journal of the Alzheimer's Association
Feb 1, 2026
INTRODUCTION: While current blood-based biomarkers for Alzheimer's disease (AD) are effective for determining amyloid beta (Aβ) pathology positivity/negativity, they are insufficient for quantifying Aβ plaque deposition. METHODS: We profiled 325 plas... read more
The myostatin protein is a potent negative regulator of skeletal muscle growth encoded by the MSTN gene. MSTN loss-of-function variants lead to a particular cattle phenotype characterized by an increase in skeletal muscle mass, known as "double muscl... read more
Journal of applied clinical medical physics
Feb 1, 2026
BACKGROUND AND PURPOSE: Kidney-ureter-bladder (KUB) radiography is a common examination that exposes patients to a higher radiation dose and increased cancer risk; therefore, it is important to estimate suitable exposure factors for each patient prio... read more
BACKGROUND: Volumetric modulated arc therapy (VMAT) machine parameter optimization (MPO) is a complex, high-dimensional problem typically solved with inverse planning solutions that are both temporally and computationally expensive. While machine lea... read more
BACKGROUND: Segmentation of intracranial hemorrhage (ICH) alongside the brain's ventricles can provide crucial information in the management stroke or traumatic brain injury (TBI). Automated computed tomography (CT) based segmentation is time-efficie... read more
BACKGROUND: Segmentation is the most effort-consuming step for magnetic resonance imaging guided adaptive radiotherapy (MRIgART). Although the segment anything model (SAM) exhibits impressive capabilities, its application in medical imaging necessita... read more
BACKGROUND: In computed tomography (CT)-guided cervical cancer brachytherapy, the manual contouring for the high-risk clinical target volume (HR-CTV) is a time-consuming and expertise-dependent process. Furthermore, automated approaches struggle with... read more
Due to the complicated physical mechanisms of topological systems and the pronounced sensitivity and intrinsic asymmetry of Fano resonance, achieving structural designs for specific high-quality topological Fano resonances is particularly challenging... read more
A multispectral reconstruction method for flame color images based on K-means clustering and backpropagation neural networks (BPNN) is proposed to overcome the low spectral resolution of temperature measurement using color RGB three-band radiation im... read more
Direct modulation lasers (DMLs) are a low-cost technology for short-reach intensity modulation and direct detection (IM/DD) systems due to their small footprint and low power consumption. However, their performance is limited by nonlinear distortion ... read more
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