Imaging-based spatial transcriptomics enables high-resolution spatial mapping of RNA species. A key challenge in imaging-based spatial transcriptomics is accurate cell segmentation to assign each RNA molecule to the right cell. Here, we present RNA2s... read more
Accurate prediction of compound-protein interactions (CPIs) is crucial for chemical biology and drug discovery. Despite recent advancements, existing deep learning (DL)-based CPI models often struggle to simultaneously achieve high generalization per... read more
These guidelines provide a clear and practical framework for the effective implementation of digital pathology (DP) in routine anatomical pathology practice. Digital pathology, defined as the digitization of microscope slide into high-resolution whol... read more
BACKGROUND: DNA sequence deep learning models can accurately predict epigenetic and transcriptional profiles, enabling analysis of gene regulation and genetic variant effects. While large-scale models like Enformer and Borzoi are trained on abundant ... read more
Scandinavian journal of trauma, resuscitation and emergency medicine
Jan 30, 2026
BACKGROUND: The gray-to-white matter ratio (GWR) on brain computed tomography (CT) is used to predict neurological outcomes after cardiac arrest. Even though automated methods, such as automatic GWR and machine learning, have been compared to manual ... read more
OBJECTIVE: Semi-automated tools used during the preliminary screening of articles in systematic reviews can start with a small set of seed articles and actively learn from human decisions to prioritise more relevant articles for subsequent screening.... read more
American journal of preventive medicine
Jan 30, 2026
INTRODUCTION: E-cigarette prevention campaigns face visibility and sustainability challenges on social media, where provaping content dominates, and coordinated opposition is common. National initiatives such as the Food and Drug Administration's The... read more
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