BACKGROUND: The glymphatic system plays a critical role in brain waste clearance and health. Diffusion tensor imaging along the perivascular space (DTI-ALPS) is an emerging approach to assess glymphatic function, but manual analysis is limited by its... read more
INTRODUCTION: Respiratory-induced artefacts cause blurring in PET images, impairing lesion identification and diagnosis. Existing correction methods exhibit limited feature learning capabilities, making it challenging to effectively eliminate artefac... read more
BACKGROUND: Artificial intelligence (AI) is increasingly being integrated into health, education, and social systems, offering new opportunities to enhance the quality of life (QoL) for individuals with intellectual disabilities (ID). Saudi Arabia ha... read more
AIM: To build a comprehensive nursing risk model for older adults inpatients with multiple chronic conditions to identify nursing risks. METHOD: This study was conducted in Sichuan Province, China from March 2020 to June 2022. We used Python to build... read more
Increases in precipitation extremes and rapid urbanization are globally reshaping urban flood risks. However, few studies jointly assess within-city exposure inequalities and green-gray infrastructure capacities at national scale. A multistage framew... read more
Carbon-based materials, such as carbon black, have emerged as prominent candidates for the cathodic electrosynthesis of H2O2 due to their low cost, durability, and ease of chemical modification. While recent advances in catalyst design and parameter ... read more
Large-scale groundwater prediction inherently involves data characterized by strong spatial and temporal heterogeneity as well as high dimensionality. Conventional data-driven approaches often struggle to effectively capture the complex and nonlinear... read more
Current opinion in structural biology
Jan 30, 2026
Proteolysis-targeting chimeras (PROTACs) and molecular glues promote targeted protein degradation by recruiting an E3 ligase to proteins of interest (POIs). An accurate 3D structure of the ternary complex formed by E3 ligase, ligand, and POI is centr... read more
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