BACKGROUND: Immune cell infiltration in the renal interstitium contributes to the progression of diabetic nephropathy (DN), yet the precise mechanisms remain incompletely unclear. METHODS: Public multi-omics datasets were integrated for comprehensive... read more
Clinical trial enrollment in oncology remains limited by increasingly complex eligibility criteria, biomarker stratification, and fragmented clinical data, contributing to prolonged recruitment timelines and low participation rates. This review exami... read more
Neoadjuvant therapy is a cornerstone of modern oncology, yet its efficacy is traditionally assessed only after treatment completion, creating a "black box" period where patients may receive ineffective, toxic therapies. This review explores the trans... read more
OBJECTIVES: Prostate cancer (PCa) diagnosis is increasingly guided by imaging, with ultrasound (US) emerging as a cost-effective and widely accessible modality. This study develops a deep learning-based classifier predicting the presence of clinicall... read more
Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology
Jan 30, 2026
Neurological disorders of the brain and spinal cord affect millions of individuals worldwide and continue to rise in prevalence. Conditions such as Alzheimer's disease, Parkinson's disease, epilepsy, spinal cord injury, and neurodevelopmental disorde... read more
Psychiatric services (Washington, D.C.)
Jan 30, 2026
OBJECTIVE: Identifying employees at risk for turnover is critical to supporting staff retention in community behavioral health organizations (CBHOs). The authors propose a method that uses machine-learning (ML) models trained with historical human re... read more
International journal of neural systems
Jan 30, 2026
Deep Learning (DL) models excel at automatically learning intricate patterns within complex data, but their black box nature undermines human trust. To address this, current validation strategies typically focus on the model itself, modifying its arc... read more
BACKGROUND: Artificial intelligence (AI) tools based on large language models (LLMs) are being increasingly used by researchers and may play a role in health-related research priority-setting exercises (RPSEs). However, little is known about how thes... read more
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