Japanese journal of clinical oncology
Jan 29, 2026
Rectal cancer management has increasingly shifted toward organ-preserving strategies that aim to maintain oncologic control while preserving bowel, urinary, and sexual functions. Although radical surgery remains highly effective, its substantial long... read more
Functionally graded surfaces and materials, featuring spatial variations in terms of composition, structure, and other properties across distance, have emerged as powerful platforms for mimicking native tissue architectures and enabling a wide range ... read more
Journal of chemical theory and computation
Jan 29, 2026
Antimicrobial peptides (AMPs) represent a promising alternative to traditional antibiotics against which many bacteria are rapidly gaining resistance. Today, databases containing tens of thousands of AMPs, along with their properties and biological a... read more
The detection of volatile organic compounds (VOCs) in urine is a noninvasive diagnostic technique with tremendous promise, holding great potential for early screening, auxiliary diagnosis, and progression monitoring of urinary system diseases. We dev... read more
BACKGROUND: Identifying eligible studies is a foundational component of systematic reviews, requiring careful interpretation of complex inclusion and exclusion criteria. Given the rapid integration of large language models (LLMs) into evidence synthe... read more
International journal of surgery (London, England)
Jan 29, 2026
OBJECTIVE: This study aimed to clarify the molecular mechanisms through which nicotine (Nic) aggravates ischemic stroke (IS), with an emphasis on inflammation and pyroptosis in Microglia. METHODS: An integrative strategy was employed, combining netwo... read more
International journal of surgery (London, England)
Jan 29, 2026
BACKGROUND: Gastroenteropancreatic neuroendocrine neoplasms (GEP-NENs) are heterogeneous tumors with rising incidence, necessitating precise preoperative grading for treatment planning. Existing imaging techniques and endoscopic biopsies often fall s... read more
International journal of surgery (London, England)
Jan 29, 2026
BACKGROUND: Tris(1,3-dichloro-2-propyl) phosphate (TDCPP) is a widely used organophosphorus flame retardant that has raised growing concern because it is persistent, can bioaccumulate, and is toxic. However, its possible role in chronic kidney diseas... read more
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