Mitochondrial and lysosomal dysfunction are central features of Parkinson's disease (PD) across major genetic forms including PRKN, SNCA, and LRRK2. We applied cell morphomics, a machine-learning-based framework combining high-content imaging with qu... read more
Radiogenomics offers a promising non-invasive approach for characterizing breast cancer (BC), yet its progress is often limited by the scarcity of cohorts containing matched imaging and multi-omics data. Recent advances in generative AI have enabled ... read more
Respiratory syncytial virus (RSV) remains the leading cause of severe respiratory infections in infants, the elderly, and the immunocompromised. Although stabilized full-length pre-fusion (pre-F) protein vaccines are promising, enhanced respiratory d... read more
Spatial and activity-dependent gene regulation in the mammalian brain requires coordinated control of RNA synthesis and degradation, yet spatially resolved measurement of RNA turnover kinetics in complex tissues remains technically challenging. Here,... read more
Robust estimation of systemic human cognitive states is critical for many applications, from simply detecting inefficiencies in human task performance to adapting the behaviors of artificial agents to improve team performance in mixed-initiative huma... read more
Passive acoustic monitoring is a valuable tool for studying elusive marine mammals, but analyzing large datasets is typically labor-intensive and costly. In this study, we piloted an automatic approach for sound analysis on extensive datasets of acou... read more
The global demand for cosmetic procedures is accelerating, with over 1.6 million aesthetic surgical procedures performed in the US in 2023. Concurrently, AI is transforming surgical practice through advanced analytics, predictive modeling, and comput... read more
BACKGROUND: The integration of AI chatbots into plastic surgery websites is now standard, providing asynchronous, real-time engagement for patients. Although promoted as scheduling and medical guidance tools, their contribution to clinical workflow i... read more
BACKGROUND: Nasolabial-fold (NLF) severity is a key indicator of facial aging and a frequent target in aesthetic treatments. The Wrinkle Severity Rating Scale (WSRS) is widely used for clinical grading but remains inherently subjective and vulnerable... read more
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