Clinical and translational gastroenterology
Jan 28, 2026
INTRODUCTION: Reliable biomarkers for the diagnosis of chronic pancreatitis (CP) and pancreatic fibrosis severity are lacking, hindering effective treatment and management. Histologic fibrosis is a hallmark of late-stage CP, but non-invasive methods ... read more
Fentanyl, an ultra-potent synthetic opioid, has traditionally been characterized by its acute toxic effects, particularly respiratory depression. However, accumulating research indicates that its neurobiological influence extends far beyond its short... read more
Cranio : the journal of craniomandibular practice
Jan 28, 2026
OBJECTIVE: To evaluate supervised machine learning (ML) models for classifying temporomandibular joint (TMJ) disc displacement on MRI using morphometric and signal intensity features. METHODS: This retrospective study analyzed 324 TMJs from 162 indiv... read more
Proceedings of the National Academy of Sciences of the United States of America
Jan 28, 2026
Understanding how animal behavior evolves remains a major challenge, with few studies linking genetic changes to differences in neural function and behavior across species. Here, we identify specific sensory adaptations associated with the emergence ... read more
Proceedings of the National Academy of Sciences of the United States of America
Jan 28, 2026
The human cell surfaceome, integral to cell communication and disease mechanisms, presents a prime target for therapeutic intervention. De novo protein binder design against these cell surface proteins offers a promising yet underexplored strategy fo... read more
Proceedings of the National Academy of Sciences of the United States of America
Jan 28, 2026
In this work, we present a type of molecular dynamics simulation that aims at finding, in a blind way, metastable states. Using only data coming from an initial unbiased simulation, and with the help of an appropriately defined loss function, we comp... read more
This study aims to quantify environmental health impacts and assess risk by understanding the disproportionate burden of infectious diseases, specifically Influenza-like Illness (ILI), across regions with varying socio-economic characteristics. We in... read more
Achieving humanlike dexterity with anthropomorphic multifingered robotic hands requires precise finger coordination. However, dexterous manipulation remains highly challenging because of high-dimensional action-observation spaces, complex hand-object... read more
Don't Miss the Future of Medicine
Join thousands of healthcare professionals staying informed about the latest AI breakthroughs in medicine. Get curated insights delivered to your inbox.