Electric field (EF) stimulation is an emerging neuromodulatory strategy for promoting the repair and functional recovery of degenerated neural networks in neurodegenerative conditions such as glaucoma. EF stimulation therapeutic potential is thought ... read more
Protein-protein interactions (PPIs) and nanobody-antigen interactions (NAIs) play essential roles in cellular function, yet accurate hotspot prediction remains challenging. We present Surf2Spot, a deep learning framework that integrates sequence embe... read more
Sensory neurons modulate organismal physiology and behavior in part by releasing neuropeptides and neurotrophins or growth factors, via the dense core vesicle (DCV) pathway. The precise matching of the sensory input to the identity of released vesicl... read more
Protein function emerges from three-dimensional structure, yet many large-scale protein prediction pipelines still rely solely on linear sequence embeddings. Although multiple structure-aware protein networks have been proposed, they often omit atom-... read more
The microbiome responds to physicochemical changes in the environment, making it a sensitive indicator of ecosystem status. Monitoring microbial communities in aquatic systems is therefore essential for understanding ecosystem health and responses to... read more
Nanopore sequencing has achieved a new standard of accuracy with the advent of R10.4.1 flow cell and high-performance Transformer-based basecalling models. However, existing signal simulators often fail to capture the complex, non-linear dynamics of ... read more
Implant-based breast reconstruction is the most common surgical option following mastectomy for breast cancer. Despite its prevalence, up to one-third of patients develop complications within two years. Existing machine-learning models for predicting... read more
Background: Automated thrombus segmentation on CT imaging could enable routine extraction of clot volume and other biomarkers in large vessel occlusion (LVO) stroke, but current deep learning models provide deterministic masks without indicating when... read more
Patient selection and enrolment into phase III randomized clinical trials (RCTs) of adjuvant cyclin-dependent kinase 4 and 6 (CDK4/6) inhibitor therapies depend on accurate risk definition. However, standard clinicopathologic criteria incompletely ca... read more
Comprehensive clinical history taking is essential for high-quality care. We hypothesized that large language models (LLMs), guided by a structured agentic framework, can efficiently obtain clinically meaningful patient histories. We developed an ite... read more
Join thousands of healthcare professionals staying informed about the latest AI breakthroughs in medicine. Get curated insights delivered to your inbox.