AI Medical Compendium

Advances in the pharmacology and mechanism of anti-skin aging in Tonifying Traditional Chinese Medicines.

Journal of ethnopharmacology Jan 25, 2026

ETHNOPHARMACOLOGICAL RELEVANCE: According to the Traditional Chinese Medicine (TCM) tenet that "internal imbalances manifest externally," skin aging reflects deficiencies in qi, blood, and organ systems-particularly the liver and kidneys. Tonifying T... read more

The predictive edge: modeling and simulation in drug product development.

Advanced drug delivery reviews Jan 25, 2026

It is well-known that drug development is challenging and a time- and resource-intensive endeavor. Historically, it has relied heavily on trial-and-error, empirical approaches that yield a low probability of success. Despite continuous efforts to imp... read more

Accurate enzyme specificity constant prediction with iESC.

Bioresource technology Jan 25, 2026

Enzyme specificity constants (ESC) are critical quantitative metrics of enzyme properties, especially the Michaelis constant (Km) and turnover number (kcat). However, traditional methods for measuring Km and kcat are laborious and time-consuming. Her... read more

Converse or reverse? Machine-learning modeling for disease progression: A study based on Alzheimer's disease continuum cohort.

NeuroImage Jan 25, 2026

INTRODUCTION: Longitudinal trajectories from healthy aging to Mild Cognitive Impairment and Alzheimer's Disease involve complex mechanisms. METHODS: We evaluated five machine learning approaches (Random Forest, Support Vector Machines, Radial Basis F... read more

Amoeba-inspired nano-robots for trace low-molecular-weight emerging contaminant removal from water.

Water research Jan 25, 2026

Trace low-molecular-weight emerging contaminants (LMWECs) in drinking water sources pose chronic health risks but remain challenging to remove using conventional treatment processes. Here, we describe an amoeba-inspired nano-robot (NRm, where m refer... read more

The OnSPARK LTC Data Platform: Leveraging interRAI to Build a Learning Health System for Long-Term Care.

Healthcare management forum Jan 25, 2026

Long-Term Care (LTC) in Canada faces persistent challenges in quality, staffing, and accountability. InterRAI assessment instruments, used nationally and internationally, provide validated scales, quality indicators, and care planning tools that supp... read more

MGM as a Large-Scale Pretrained Foundation Model for Microbiome Analyses in Diverse Contexts.

Advanced science (Weinheim, Baden-Wurttemberg, Germany) Jan 25, 2026

Microbial communities are integral to human health, biotechnology, and environmental systems, yet their analysis is hindered by data heterogeneity and batch effects across studies. Traditional supervised methods often fail to capture universal patter... read more

The Emerging Role of Artificial Intelligence in the Assessment of Valvular Heart Disease with Cardiac Imaging.

Current cardiology reports Jan 25, 2026

Image-space compensation of inter-crystal scattering in PET using a neural network based filter.

EJNMMI physics Jan 25, 2026

BACKGROUND: In positron emission tomography (PET), gamma photons arriving at the detector ring may undergo one or more Compton scattering events, potentially reaching a different scintillation crystal than its initial interaction point. This phenomen... read more

An Artificial Intelligence-Driven Platform for Practice Question Generation.

Academic medicine : journal of the Association of American Medical Colleges Jan 25, 2026

PROBLEM: High-stakes licensing exams such as the USMLE play a critical role in medical education, influencing both trainee progression and patient outcomes. Access to high-quality board preparation resources is uneven and often cost-prohibitive, disp... read more

Artificial Intelligence Medical Compendium