Despite the considerable expansion of bioimage analysis as a subfield of biomedical sciences, there is an ongoing need for comprehensive image analysis pipelines to address specific biological inquiries. In the tumor microenvironment, the extracellul... read more
Pleural and ascitic cytology is essential for diagnosing metastatic cancer and predicting tumor origin, yet microscopic observation alone often leads to low accuracy and observer variability. Although deep learning shows great potential in pathology,... read more
Artificial intelligence (AI) is quickly becoming a revolutionary and game-changing tool in modern oncology, with promising uses in early diagnosis and drug discovery. Machine learning (ML), deep learning (DL), reinforcement learning (RL), natural lan... read more
BACKGROUND/OBJECTIVES: The consistency of pituitary adenoma (PA) significantly impacts surgical difficulty and the extent of resection. Machine learning (ML) and radiomics have emerged as quantitative tools to predict tumor firmness from MRI-derived ... read more
BACKGROUND: Cognitive fatigue is a frequently reported and debilitating symptom of long COVID, yet effective therapeutic interventions remain limited. Anodal transcranial direct current stimulation (tDCS) over the dorsolateral prefrontal cortex (dlPF... read more
BACKGROUND: Mass spectrometry-based proteomics enables high-throughput quantification of thousands of proteins in clinical samples, fueling biomarker discovery for disease diagnosis and prognosis. However, leveraging complex proteomic profiles for pr... read more
OBJECTIVE: Lung neuroendocrine neoplasms (L-NENs) are increasingly recognized, yet reliable preoperative assessment of the Ki-67 proliferation index remains invasive and subject to sampling variability. We aimed to develop and validate a clinical-rad... read more
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