AI Medical Compendium

Graph neural network-guided identification and biological evaluation of potential AKT1 inhibitors for triple-negative breast cancer.

Computers in biology and medicine Jan 22, 2026

Triple-negative breast cancer (TNBC) presents a significant therapeutic challenge due to its aggressive behavior and lack of targeted therapies. The PI3K/AKT/mTOR signaling pathway, particularly AKT1, is frequently dysregulated in TNBC, driving disea... read more

Exploration Novel Therapeutic Targets for Periodontitis via Stress Granules Biomarkers.

International dental journal Jan 22, 2026

BACKGROUND: Periodontitis (PD) is associated with stress granules (SGs), which are involved in cellular stress responses. Identifying biomarkers related to SGs in PD is key to grasping its pathogenesis and devising novel therapeutic approaches. METHO... read more

Panoramic Landmarks: Comparing LLM-Assisted, Manual Tracing, and Self-Directed Learning in Dental Education.

International dental journal Jan 22, 2026

BACKGROUND: Accurate identification of anatomical landmarks on panoramic radiographs is a foundational yet challenging skill in dentistry. Traditional didactic teaching often requires supplementation to achieve proficiency. This study evaluates and c... read more

Human-GenAI-based agent collaboration: How employee perceptions shape knowledge sharing, thriving, and well-being.

Acta psychologica Jan 22, 2026

The growing pace of the introduction of generative artificial intelligence (GenAI) into organizational processes is changing the way workers cooperate with technology. Based on Social Exchange Theory, we propose that the perception of employees regar... read more

Teacher charisma and AI-mediated education: Effects on EFL learners' attitudes and self-efficacy.

Acta psychologica Jan 22, 2026

Although Artificial Intelligence (AI) is being rapidly incorporated into the education sector, a glaring gap remains in understanding how AI-mediated education (AME) interacts with vital human components, including teacher influence, in shaping learn... read more

Recent developments in terpenoid biosynthesis for sustainable biofuels: from bottlenecks to emerging convergent technologies.

Current opinion in biotechnology Jan 22, 2026

Terpenoid-based biofuels represent a sustainable alternative to fossil fuels with superior energy densities and combustion properties. However, achieving industrial-scale production requires overcoming multiple bottlenecks: heterologous enzyme incomp... read more

Revealing the hidden patterns of shark and ray diversity over the past 145 million years.

Current biology : CB Jan 22, 2026

Neoselachians (a monophyletic group including modern sharks, rays, and skates and their extinct relatives)1,2 have an extensive fossil record and a long evolutionary history,1,2,3 with over 1,100 extant species today.4 Previous reconstructions of the... read more

Science, Quality and Value of Laboratory Medicine.

Clinical chemistry and laboratory medicine Jan 22, 2026

The Meeting on Science, Quality and Value of Laboratory Medicine was held on 11 December 2025 in Padua, immediately preceding the 7th European Federation of Clinical Chemistry and Laboratory Medicine (EFLM) Conference on the Preanalytical Phase. For ... read more

Detection and imaging of chemicals and hidden explosives using terahertz time-domain spectroscopy and deep learning.

Light, science & applications Jan 22, 2026

Detecting concealed chemicals and explosives remains a critical challenge in global security. Terahertz time-domain spectroscopy (THz-TDS) offers a promising non-invasive and stand-off detection technique owing to its ability to penetrate optically o... read more

Training and external validation of machine learning supervised prognostic models of upper tract urothelial cancer (UTUC) after nephroureterectomy.

Scientific reports Jan 22, 2026

Artificial Intelligence Medical Compendium