The evolutionary histories of species have been shaped by genomic, environmental, and morphological variation. Understanding the interactions among these sources of variation is critical to infer accurately the biogeographic history of lineages. Here... read more
The escalating crisis of antimicrobial resistance poses a devastating and immediate threat to human life. Antimicrobial peptides (AMPs) are a promising antibiotic substitute to combat antimicrobial resistance. Compared with the traditional wet-lab sc... read more
Live cell imaging is uniquely placed to study cell behavior as it preserves spatial context and enables non-destructive observations over time. Integrating live cell imaging and molecular phenotypes with single-cell resolution is key to uncovering th... read more
Accurate prediction of antibody-antigen (Ab-Ag) complexation is crucial for understanding immune responses, diagnostics, and the development of therapeutic antibodies. While molecular docking generates conformations, current scoring functions struggl... read more
The human genome is partitioned at different levels of 3D genome organization, with topologically associating domains (TADs) being among the most well-known and biologically important structures. TAD boundary disruption is associated with a wide rang... read more
Rapid and accurate detection of electrographic seizures is critical for both clinical diagnosis and neuroscience research. Although seizure identification is commonly performed in the time domain, analysis in the time-frequency domain provides a more... read more
Molecular dynamics (MD) simulations yield atomic-level insights into molecular motion but struggle to reach the long timescales needed for rare events due to prohibitive computational costs. Generative machine-learning models (e.g., diffusion models ... read more
Previous studies exploring human sweat ducts as biological antennas in the sub-THz range have shown that the electromagnetic (EM) response of the skin is modulated by the person's mental and physical stress. These findings naturally raised hopes of a... read more
Despite a decade of immunotherapy, treatment selection in non-small cell lung cancer (NSCLC) still relies on subgroup analyses and clinical scores. I3LUNG (NCT05537922) is currently the largest international, real-world, multimodal, artificial intell... read more
Motivation: Medical documents are a crucial resource for medical research around the world. While troves of valuable health data exist, they are largely computationally inaccessible as hard copies of unstructured text, often with degraded quality due... read more
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