Canine mammary tumors (CMTs) are the most common neoplasms in intact female dogs, yet early detection remains challenging due to the lack of clinically validated, noninvasive biomarkers. This study aimed to develop a noninvasive diagnostic model for ... read more
Vibrio infections progress rapidly with high mortality, yet current diagnostics fail to meet the critical need for rapid, accurate, and field-deployable detection. To bridge this gap, we present a bioreceptor-free, AI-powered surface-enhanced Raman s... read more
The American journal of gastroenterology
Jan 21, 2026
INTRODUCTION: Clostridioides difficile infection (CDI) present a significant challenge in patients with inflammatory bowel disease (IBD), with high recurrence rates and complications. Predicting recurrent CDI (rCDI) in IBD patients is crucial for imp... read more
DNA-based storage offers exceptional information density, durability, and energy efficiency compared to conventional digital media, yet practical implementation faces challenges including high synthesis costs, sequencing errors, and slow access speed... read more
Optical sensor arrays have emerged as a powerful paradigm for high-throughput, multiplexed analysis, overcoming the limitations of traditional single-analyte sensing by leveraging cross-reactive elements to generate distinct multidimensional response... read more
BACKGROUND: Peri-implantitis is a common implant complication requiring early detection to prevent bone loss and implant failure. Deep learning models show promise for enhancing radiographic diagnosis. OBJECTIVES: This review systematically evaluated... read more
Journal of chemical information and modeling
Jan 21, 2026
Accurate prediction of protein-ligand binding affinity is essential in drug discovery. However, the limited availability and high cost of experimentally resolved protein-ligand complex structures significantly hinder the generalizability and broad ap... read more
Combination therapy is widely used in clinical practice, rendering accurate prediction of drug-drug interactions (DDIs) essential for treatment safety and efficacy. This paper proposes PTET-DDI, a novel dual-channel framework that synergizes chemical... read more
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