Prostaglandin receptors are pharmacologically validated targets with implications in several medical indications, including glaucoma, cardiac cyanotic disease, pulmonary hypertension, oncology, and various rare diseases. In this study, we developed a... read more
With manual update, progress monitoring of a construction project is notably challenging due to its labor-intensive and time-consuming nature. The issue of manual update has been proposed to be alleviated by automatic update, but most existing AI-bas... read more
Accurate and scalable taxonomic classification is essential for biodiversity research, supporting systematic species identification across multiple hierarchical ranks. However, current image-based classification methods often fail to enforce taxonomi... read more
The development of accurate digital models (DMs) for physical systems requires virtual representations that faithfully capture the underlying physics of the system or equipment being represented. Physics-based DMs provide reliable predictions only wh... read more
When picking red pepper clusters, occlusion and overlapping fruit are major challenges hindering the development of intelligent red pepper cluster picking robots. To achieve accurate and efficient picking, we proposed a lightweight red pepper cluster... read more
Deploying deep learning-based object detectors on low-compute edge AI SoCs remains challenging, as real-world performance depends on factors beyond nominal TOPS ratings, including architectural design, memory bandwidth, and system-level contention. T... read more
This study utilized a novel Proximity Barcoding Assay to perform high-resolution proteomic profiling of individual plasma extracellular vesicles from 85 patients with advanced high-grade serous ovarian carcinoma (OC) and 95 healthy controls (HC). Sin... read more
BACKGROUND: Despite increased understanding of psoriasis pathogenesis, molecular classification of clinical phenotypes and disease severity is poorly defined. Knowledge gaps include whether molecular endotypes of psoriasis underlie distinct clinical ... read more
Three-dimensional mapping of retinal microvasculature is essential for monitoring systemic vascular health. Existing methods rely heavily on manual annotation or training-intensive deep learning models that lack generalizability. Here we report RADAR... read more
Accurate quality assessment is critical for computational prediction and design of RNA three-dimensional (3D) structures, yet it remains a significant challenge. In this work, we introduce RNArank, a deep learning-based approach to both local and glo... read more
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