Breast cancer remains a critical global health challenge, with timely and reliable diagnosis being essential for improving clinical outcomes. Although recent advances in computer aided diagnosis (CAD) have increasingly adopted deep learning, many exi... read more
Behaviours are adaptive traits evolving through natural selection. Crucially, the genetic, molecular and neural modifications that shape behavioural innovations are poorly understood1. Here, we identify specialized adaptations linked to the evolution... read more
Earth's early mantle probably existed as a deep, vigorously convecting magma ocean, and its solidification is considered central to the long-term chemical and dynamical evolution of the planet. Yet a notable uncertainty is the grain size of bridgmani... read more
Urban public safety is shaped by the interaction of environmental, infrastructural, and social risks that often overlap across rapidly urbanizing regions. This study develops an integrated framework combining Geographic Information Systems (GIS), Mul... read more
OBJECTIVES: Artificial intelligence (AI) has been applied in a number of breast screening settings with favourable results. While there are a limited number of studies exploring patient attitudes on the use of AI in breast screening, none to date hav... read more
Accurate quality assessment is critical for computational prediction and design of RNA three-dimensional (3D) structures, yet it remains a significant challenge. In this work, we introduce RNArank, a deep learning-based approach to both local and glo... read more
Three-dimensional mapping of retinal microvasculature is essential for monitoring systemic vascular health. Existing methods rely heavily on manual annotation or training-intensive deep learning models that lack generalizability. Here we report RADAR... read more
BACKGROUND: Despite increased understanding of psoriasis pathogenesis, molecular classification of clinical phenotypes and disease severity is poorly defined. Knowledge gaps include whether molecular endotypes of psoriasis underlie distinct clinical ... read more
This study utilized a novel Proximity Barcoding Assay to perform high-resolution proteomic profiling of individual plasma extracellular vesicles from 85 patients with advanced high-grade serous ovarian carcinoma (OC) and 95 healthy controls (HC). Sin... read more
BACKGROUND: With the high pace of development in technology worldwide, Artificial intelligence (AI) has given a new horizon to the world of medicine and dentistry. Numerous research studies have been carried out over the past decade that have assesse... read more
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