Dengue (DENV), an RNA virus, remains a significant global health threat, particularly in developing regions, with no widely effective antiviral therapy available. The CRISPR-Cas13b system, specifically the PspCas13b subtype, has emerged as a promisin... read more
Objective: To evaluate the performance of Thermalytix, an artificial intelligence-enhanced breast thermal imaging analysis software, against unaided manual interpretation of thermographic images. Methods: In this multi-reader study, thermal imaging d... read more
Whole-brain simulations are a valuable tool for gaining insight into the multiscale processes that regulate brain activity. Due to the complexity of the brain, it is impractical to include all microscopic details in a simulation. Hence, researchers o... read more
Musical performances, particularly in drumming, are characterized not only by their structured rhythmic patterns but also by the subtle variations in timing and amplitude series that create expressive complexity. This study proposes a neural-inspired... read more
Spontaneous neural activity is often dismissed as noise, yet predicting its future evolution remains difficult, especially across recording preparations. We study transfer between in vitro and in vivo multineuronal spike trains with a Transformer tha... read more
Digital pathology using whole slide imaging (WSI) and artificial intelligence (AI) has the potential to transform diagnostic workflows, but adoption remains limited by technical complexity and scalability. We developed the Computational Renal Patholo... read more
AI agents promise to empower biomedical discovery, but realizing this promise requires the ability to complete transparent, long-horizon analyses using tools. Agents must make intermediate decisions explicit, and validate each decision and output aga... read more
Ecotoxicological tests with soil organisms, such as the collembolan Folsomia candida, are essential for assessing chemical risks in terrestrial ecosystems. However, the current Organization for Economic Co-operation and Development (OECD) 232 reprodu... read more
Understanding the role of tertiary lymphoid structures (TLS) is crucial in non-small cell lung cancer (NSCLC), as they are associated with patient prognosis and treatment outcomes. Specific cellular ecosystems that originate anti-tumor activity or pr... read more
Accurate trachea segmentation from computed tomography (CT) is a prerequisite for image- guided airway assessment, toward precision tracheostomy planning and safe endotracheal tube placement. Trachea-specific delineation remains challenging due to el... read more
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