Susceptibility to epileptogenesis varies in humans and outbred mouse strains. We hypothesized that baseline sleep abnormalities increase susceptibility to epileptogenesis following Kainic acid (KA) and abnormal circadian rhythm or sleep homeostasis (... read more
Background: Live-cell fluorescence microscopy enables the study of dynamic cellular processes. However, fluorescence microscopy can damage cells and disrupt these dynamic processes through photobleaching and phototoxicity. Reducing light exposure mit... read more
Building a virtual cell that simulates cellular behavior in silico is a central goal of computational biology. We introduce CellFluxV2, an image-generative model that predicts how cell morphologies change in response to chemical and genetic perturbat... read more
3' untranslated regions (3' UTRs) serve as regulatory platforms that modulate translation, mRNA localization, and stability through the binding of regulators, such as RNA-binding proteins (RBPs) and miRNAs, in a sequence-specific manner. These vital ... read more
Echo state networks (ESNs) are a class of recurrent neural networks in which only the readout layer is trainable, while the recurrent and input layers are fixed. This architectural constraint enables computationally efficient processing of time-serie... read more
PURPOSE: To provide a historical review tracing the evolution of oculomics, the study of ocular biomarkers of systemic disease, from early clinical observations to the emergence of advanced imaging and artificial intelligence (AI) technologies over t... read more
Accurate assessment of animal behavior is limited by manual video observation. Here, we demonstrate that deep learning-based analysis of multi-site electromyograms enables classification of behavioral states. Electromyograms were recorded from five m... read more
Food research international (Ottawa, Ont.)
Jan 20, 2026
The quality degradation of frozen meat during storage is mainly attributed to oxidative reactions in lipids and proteins. This study aimed to evaluate lipid and protein oxidation in frozen-thawed chicken meat by employing hyperspectral imaging (HSI).... read more
Food research international (Ottawa, Ont.)
Jan 20, 2026
This study was conducted to investigate the potential use of Fourier-transform near-infrared (FT-NIR) spectroscopy combined with machine learning (ML) algorithms to accurately identify three foodborne pathogens, including Salmonella spp., Listeria mo... read more
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