Snakebite is a neglected public health problem that results in significant morbidity and mortality, necessitating the World Health Organization (WHO) to develop a snakebite roadmap that aimed to halve the burden of snakebite envenoming (SBE) by 2030.... read more
ObjectiveHigh-frequency oscillations (HFOs) are highly specific biomarkers of epileptogenic tissue, yet their noninvasive localization remains challenging due to their brief duration, low amplitude, and poor signal-to-noise ratio. Here, we introduce ... read more
Clinical trial statistical programming requires 12-24 FTE-months for a typical Phase 3 study, producing 100-500 tables, listings, and figures (TLFs) across 8-15 ADaM domains. Modern AI coding agents (Augment Code, Claude Code, Cline, Cursor) demonstr... read more
IntroductionAcute myocardial infarction (AMI) remains a leading cause of mortality, with the coexistence of other conditions (i.e., multimorbidity) complicating management and outcomes. Currently, healthcare providers see major challenges in consider... read more
BackgroundCT scans are the gold-standard diagnostic test for pulmonary embolisms (PE). Despite stable PE prevalence, CT use is rising in emergency departments (EDs), suggesting test overuse. Current methods for measuring test yield are error-prone or... read more
BackgroundAccurate etiologic classification of mitral valve (MV) is essential for guiding clinical management but remains dependent on expert visual interpretation. Despite advances in artificial intelligence (AI)-based quantitative analysis, automat... read more
Traditional surgical training relies heavily on hands-on experiences gained through relatively infrequent procedures during apprenticeships. Recently, postoperative review has become a valuable supplement to this model, offering learning opportunitie... read more
Artificial intelligence models in healthcare often fail to improve patient outcomes despite strong predictive performance because they are frequently developed with limited understanding of clinical workflows and system implementation. We demonstrate... read more
BackgroundThe pancreas is essential for metabolic homeostasis. Alterations in morphology and parenchymal integrity may impact proper function but are not routinely used for risk stratification. Here, we propose an AI-pipeline to quantify pancreas vol... read more
ImportanceVision-language models (VLMs) enable generalist multimodal reasoning, but their ability to resolve brief, low-contrast cues in surgical video without task-specific training is uncertain. Autonomous artificial intelligence (AI) agents offer ... read more
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