IntroductionAcute myocardial infarction (AMI) remains a leading cause of mortality, with the coexistence of other conditions (i.e., multimorbidity) complicating management and outcomes. Currently, healthcare providers see major challenges in consider... read more
Data-driven sleep research relies on polysomnography data from various public repositories and vendor systems. Yet the lack of standardized access methods creates substantial barriers to multi-dataset research, method reuse, and reproducibility. We p... read more
The utilization of continuous ECG monitoring has become an integral part of modern hospital-based care. However, missing data presents significant challenges in deploying real-time ECG-based predictive systems. Research on the implementation of imput... read more
Traditional surgical training relies heavily on hands-on experiences gained through relatively infrequent procedures during apprenticeships. Recently, postoperative review has become a valuable supplement to this model, offering learning opportunitie... read more
BackgroundThe pancreas is essential for metabolic homeostasis. Alterations in morphology and parenchymal integrity may impact proper function but are not routinely used for risk stratification. Here, we propose an AI-pipeline to quantify pancreas vol... read more
ImportanceVision-language models (VLMs) enable generalist multimodal reasoning, but their ability to resolve brief, low-contrast cues in surgical video without task-specific training is uncertain. Autonomous artificial intelligence (AI) agents offer ... read more
Artificial intelligence models in healthcare often fail to improve patient outcomes despite strong predictive performance because they are frequently developed with limited understanding of clinical workflows and system implementation. We demonstrate... read more
Membrane segmentation is an essential task in the workflow for processing cryo-electron tomography data. Recently, machine learning algorithms have successfully been adopted to perform membrane segmentation. However, the performance of these approach... read more
Background/ObjectivesHead and neck cancer (HNC) represents the seventh most common cancer diagnosis globally, yet current treatments, including surgery, radiation, and immunotherapy, have shown limited improvement in outcomes. Drug repurposing offers... read more
Protein thermal stability, quantified by the change in Gibbs free energy ({Delta}{Delta}G) upon mutation, is critical for drug design and enzyme engineering. Current multi-modal deep learning models, despite integrating sequence, often struggle with ... read more
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