BACKGROUND: Post-percutaneous coronary intervention (PCI) Murray's law-based quantitative flow ratio (μFR) is associated with long-term clinical outcomes. A tool capable of accurately predicting post-PCI μFR before intervention could support procedur... read more
Real-time monitoring of total organic carbon (TOC) is essential for assessing water quality, optimizing treatment processes, and safeguarding aquatic ecosystems. This study reports the development of a compact LED-SiPM fluorescence sensor, integrated... read more
Gynecologie, obstetrique, fertilite & senologie
Jan 17, 2026
Cardiotocography (CTG) is defined as the simultaneous recording of fetal heart rate and uterine contractions. It is used worldwide during labour to assess foetal well-being and to detect early signs of hypoxia. However, its interpretation relies main... read more
Chronic kidney disease (CKD) is a leading cause of death worldwide. Currently available drugs slow but do not cure or prevent progression to end-stage kidney disease. Unfortunately, dialysis and kidney transplant not only pose severe lifestyle constr... read more
OBJECTIVE: Recent advances in language models have shown potential to adapt professional-facing biomedical literature to plain language, making it accessible to patients and caregivers. However, their unpredictability and high potential for harm in t... read more
International journal of pharmaceutics
Jan 17, 2026
Creating high-quality datasets for training machine learning models in specialized domains like pharmaceutical research is often constrained by the manual effort required to extract and compute critical parameters from heterogeneous literature. A nov... read more
Deep learning is revolutionizing enzyme engineering through efficient residue redesign. Leveraging deep learning for enzyme engineering, we redesigned a pectinase using ProteinMPNN guided by multiple sequence alignment. Our top-performing variant, DS... read more
INTRODUCTION: Accurate cell type annotation remains a major bottleneck in plant single-cell RNA sequencing (scRNA-seq), where existing tools are often adapted from animal studies and perform sub-optimally on plant data. The lack of plant-specific com... read more
BACKGROUND: Geriatric depression is highly prevalent yet under-recognized, severely affecting older adults' quality of life and social functioning. There is an urgent need for individualized early prediction tools. While deep learning (DL) holds pote... read more
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