AI Medical Compendium

The Role of Chemical Engineers in the Pharmaceutical Industry.

Annual review of chemical and biomolecular engineering Jan 21, 2026

Chemical engineers have played a vital role in the pharmaceutical industry for more than a century, bridging the gap between scientific discovery and large-scale drug manufacturing. This review examines the evolution in the role of chemical engineers... read more

MolCluster: An Unsupervised Framework for Multiscale Molecular Representations with Physically Consistent Resolution Control.

Journal of chemical theory and computation Jan 21, 2026

Coarse-grained (CG) modeling simplifies molecular systems by mapping groups of atoms into representative particles, but traditional approaches depend on fixed rules and struggle to handle diverse chemical structures. Supervised CG methods further suf... read more

Machine learning using entropy-based texture features from MRI to differentiate histological subtypes of non-small cell lung cancer identified as metabolically active on PET/MRI.

PloS one Jan 21, 2026

Texture analysis is a foundational approach in imaging studies and demonstrates excellent diagnostic performance, with radiomic analysis being the most widely used method. New approaches to texture analysis continue to be developed. However, magnetic... read more

Improving the measurement resolution in BOTDR sensor with optimized wavelet denoising strategy.

PloS one Jan 21, 2026

Signal averaging imposes a significant trade-off between measurement time and measurand resolution in a sub-meter differential cross-spectrum Brillouin optical time domain reflectometry (DCS-BOTDR). This article introduces an optimized post-processin... read more

An integrative multiomics random forest framework for robust biomarker discovery.

GigaScience Jan 21, 2026

BACKGROUND: High-throughput technologies now produce a wide array of omics data, from genomic and transcriptomic profiles to epigenomic and proteomic measurements. Integrating multiple omics layers measured on the same samples can reveal cross-layer ... read more

Deformable image registration using multi-resolution vision Transformer for cardiac motion estimation.

Physics in medicine and biology Jan 21, 2026

Objective.Deformable registration plays a crucial role in motion estimation from a sequence of cardiac magnetic resonance (CMR) imaging, which is good for the diagnosis and treatment of heart diseases. To address the challenges posed by intensity inh... read more

Semi-supervised learning for dose prediction in targeted radionuclide therapy: a synthetic data study.

Physics in medicine and biology Jan 21, 2026

Objective.Accurate and personalized radiation dose estimation is crucial for effective targeted radionuclide therapy (TRT). Deep learning (DL) holds promise for this purpose. However, current DL-based dosimetry methods require large-scale supervised ... read more

Theoretical investigation of the excited-state dynamics in the CH4 + O(3P) → CH3 + OH reaction.

The Journal of chemical physics Jan 21, 2026

In combustion processes, particularly in systems involving reactive oxygen species (ROS), the role of electronically excited states has become a critical research frontier. This study employs the benchmark combustion reaction CH4 + O(3P) → CH3 + OH a... read more

The association of environmental exposure with multiple sclerosis severity score: A study based on sequential data modeling.

International journal of medical informatics Jan 21, 2026

Introduction Multiple Sclerosis (MS) is a chronic neuroinflammatory disease influenced by clinical, demographic, and environmental factors. Predicting MS progression is challenging due to the disease's heterogeneity. This study aimed to apply Artific... read more

A comparative evaluation of handling missing data points and modalities in electronic health records.