Sense of Joint Agency (SoJA), is the feeling of control experienced by humans for their own, as well as their partner's actions, when acting in joint action with others. SoJA is ubiquitous in human-human interaction. Therefore, it is both interesting... read more
Enhancing enzyme thermostability is crucial for industrial applications requiring robust performance under extreme conditions. Structure-based protein design models excel at improving thermal stability but often compromise enzymatic activity, while s... read more
Phenanthrene (PHE), a representative polycyclic aromatic hydrocarbon, readily bioaccumulates in soil organisms and poses substantial ecological risks. However, accurately predicting PHE toxicity across heterogeneous soils remains challenging due to c... read more
Machine learning (ML) approaches have drastically advanced the exploration of structure-property and property-property relationships in computer-aided drug discovery. A central challenge in this field is the identification of molecular descriptors th... read more
BACKGROUND: Cardiometabolic multimorbidity (CMM) is the simultaneous manifestation of multiple cardiovascular and metabolic diseases, and it has arisen as a substantial worldwide healthcare issue. The stress-hyperglycemia ratio (SHR) represents a nov... read more
INTRODUCTION: Systemic inflammation has been identified as a key factor in neurodegeneration but the value of circulating inflammatory proteins in dementia risk prediction and their causal role has not been elucidated. METHODS: We leveraged proteomic... read more
Active, student-centred teaching strategies are increasingly being adopted to bridge the gap between biomedical knowledge and clinical performance in health-profession education. This systematic review and meta-analysis aims to evaluate the comparati... read more
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