Proteins execute cellular functions through a structural continuum ranging from stable, folded domains to highly dynamic intrinsically disordered regions (IDRs). Conformational ensembles represent the set of three-dimensional structures a protein ado... read more
Numerous applications in research and medicine rely on reliable identification and quantification of virus-infected cells. Current methods either apply reporter viruses, that often differ from clinical isolates (e. g. cell tropism, immune evasion) or... read more
Three-dimensional electron microscopy (3D EM) enables the quantitative analysis of cellular ultrastructure. However, large-scale segmentation of whole-cell volumes poses a significant challenge, especially in biologically diverse systems. Unlike medi... read more
Accurately predicting how amino acid substitutions alter protein function is a central challenge in biology, with applications from interpreting disease variants to engineering vaccines and therapeutic proteins. We introduce HERMES, a family of fast,... read more
Vision-language models (VLMs) have advanced rapidly, but their ability to capture spatial relationships remains a blindspot. Current VLMs are typically built with contrastive language-image pretraining (CLIP) style image encoders. The training recipe... read more
Parkinson's disease (PD) and Alzheimer's disease (AD) are the two most prevalent and incurable neurodegenerative diseases (NDs) worldwide, for which early diagnosis is critical to delay their progression. However, the high dimensionality of multi-met... read more
Large Language Models (LLMs) are increasingly adopted in healthcare to support clinical decision-making, summarize electronic health records (EHRs), and enhance patient care. However, this integration introduces significant privacy and security chall... read more
Text-to-image person re-identification (TIReID) aims to retrieve person images from a large gallery given free-form textual descriptions. TIReID is challenging due to the substantial modality gap between visual appearances and textual expressions, as... read more
Underwater imaging is fundamentally challenging due to wavelength-dependent light attenuation, strong scattering from suspended particles, turbidity-induced blur, and non-uniform illumination. These effects impair standard cameras and make ground-tru... read more
Recent video generation models have revealed the emergence of Chain-of-Frame (CoF) reasoning, enabling frame-by-frame visual inference. With this capability, video models have been successfully applied to various visual tasks (e.g., maze solving, vis... read more
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