BackgroundDisc degeneration is the primary cause of low back pain, although the disc itself is not usually the source of the pain. Instead, it can lead to various clinically significant conditions that cause pain. However, there are no objective meas... read more
Aging is often accompanied by cognitive decline, but the extent, timing, and severity of this process is subject to large inter-individual variability. Predicting cognitive decline along a continuum, encompassing healthy age-related decline, mild cog... read more
Pathology classification of cancer tumor subtypes and benign tumors can be difficult due to cellular heterogeneity and similar morphological features. Renal Cell Cancer (RCC) poses a major challenge for uropathologists as advanced RCC is often incide... read more
BackgroundThe accuracy and safety of generating medication orders by large language models (LLMs) must be demonstrated. Without standardization, performance evaluation is limited to time and resource-intensive clinician grading. This evaluation aimed... read more
Epidemiologists often report associations between cognitive functioning and bodily physiology in older adults, but the strength and drivers of this relationship remain unclear. Which systems - from body composition to cardiovascular, pulmonary, renal... read more
BackgroundBody composition strongly influences clinical outcomes in older adults, yet body mass index (BMI) lacks discriminatory power, and standard tools such as bioelectrical impedance analysis (BIA), dual-energy X-ray absorptiometry are not routin... read more
The growth of generative AI and easily available Open Access health datasets has transformed researcher productivity, leading to an explosion in publications that has in part been attributed to paper mills (organisations that provide manuscripts for ... read more
PurposeMELD Graph is a state-of-the-art artificial intelligence (AI) model for automated detection of focal cortical dysplasia (FCD), but its performance remains limited, highlighting the need to investigate which aspects of the pipeline affect its a... read more
Brain tumors are among the most lethal cancers with gliomas representing the most morphologically complex type. Precise and time efficient glioma segmentation and classification are essential for accurate diagnosis, treatment planning, and patient mo... read more
BackgroundSystemic infections are a leading cause of hospitalization and death among patients with cirrhosis. Timely and accurate infection identification is essential for both clinical care and the development of predictive models. However, existing... read more
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