AI Medical Compendium

Longitudinal effects ambient AI scribe use on documentation burden and financial productivity: A quasi-experimental study

medRxiv Jan 14, 2026

BackgroundArtificial intelligence (AI) scribes have the potential to reduce documentation burden. Previous studies have mostly relied on aggregated, vendor-provided (e.g., Epics Signal) outcome measures, potentially obfuscating the true effect of AI ... read more

health informatics

Integrative Multi-Omics Analysis Reveals Novel Molecular Signatures, Disease Stratification and Therapeutic Opportunities in Primary Ciliary Dyskinesia: First AI-ML empowered platform towards precision medicine targeting human ciliopathies

medRxiv Jan 14, 2026

Primary ciliary dyskinesia (PCD) belongs to the group of rare genetic disorders that is extremely hard to diagnose and treat. Current diagnostic modalities detect only 70% of cases and are technically demanding. It necessitates novel computational ap... read more

health informatics

Association between cognitive status and structural brain changes in Alzheimer's disease: Clinical implication of lightweight deep learning-aided diagnosis.

European journal of radiology Jan 14, 2026

BACKGROUND: The complex brain changes involved in Alzheimer's disease (AD) development constitute a high-dimensional nonlinear feature space where deep learning (DL) classification/diagnosis may be advantageous over classical non-learning methods. Ho... read more

Deciphering the 3D genome organization across species from Hi-C data.

Nucleic acids research Jan 14, 2026

3D genome organization is essential for gene regulation, yet in various species it is driven by different biological mechanisms. Species-specific factors and DNA sequences influence chromatin folding, complicating cross-species comparisons. Leveragin... read more

A predictive framework for stop-loss variants with C-terminal extensions.

Nucleic acids research Jan 14, 2026

Stop codons dictate translation termination, and variants occurring at these sites can result in stop-loss variants, leading to C-terminal extensions with significant functional consequences. Despite their clinical relevance, existing prediction tool... read more

Initial diagnosis and management of acute ischemic stroke: recent update and future direction.

Clinical and experimental emergency medicine Jan 14, 2026

Acute ischemic stroke (AIS) outcomes depend critically on rapid, accurate early diagnosis in the emergency department. Traditional prehospital tools and large vessel occlusion focused scales aid triage, but have limited ability to distinguish ischemi... read more

Machine Learning-Based Clusters of Vital Signs and Lactate Levels Predict Vasopressor Use in Sepsis.

Clinical and experimental emergency medicine Jan 14, 2026

OBJECTIVE: Sepsis remains a major clinical challenge because of its complex, heterogeneous, and multidimensional clustering patterns. This study aimed to investigate the association between vasopressor administration and machine learning-derived clus... read more

Application of Artificial Intelligence in the Diagnosis and Treatment of Moyamoya Disease: Current Status, Challenges, and Future Prospects.

The neurologist Jan 14, 2026

BACKGROUND: Various artificial intelligence-based medical technologies have been used for diagnosing and treating diseases. Although moyamoya disease (MMD) poses a significant threat to the lives of patients, artificial intelligence (AI) use in MMD i... read more

Chronic pain and the limits of artificial intelligence: why expert knowledge matters.

Pain Jan 14, 2026

Artificial intelligence in metabolic dysfunction-associated steatotic liver disease: Transforming diagnosis and therapeutic approaches.

World journal of gastroenterology Jan 14, 2026

Metabolic dysfunction-associated steatotic liver disease (MASLD) is an increasingly prevalent condition associated with hepatic complications and cardiovascular and renal events. Given its significant clinical impact, the development of new strategie... read more

Artificial Intelligence Medical Compendium