PurposeMELD Graph is a state-of-the-art artificial intelligence (AI) model for automated detection of focal cortical dysplasia (FCD), but its performance remains limited, highlighting the need to investigate which aspects of the pipeline affect its a... read more
Brain tumors are among the most lethal cancers with gliomas representing the most morphologically complex type. Precise and time efficient glioma segmentation and classification are essential for accurate diagnosis, treatment planning, and patient mo... read more
BackgroundSystemic infections are a leading cause of hospitalization and death among patients with cirrhosis. Timely and accurate infection identification is essential for both clinical care and the development of predictive models. However, existing... read more
Patellofemoral pain (PFP) is a common running related injury associated with several biomechanical factors such as altered kinematics and kinetics across lower extremity joints. Prior research suggests mechanisms for PFP may differ within those affec... read more
Severe motor impairments such as amyotrophic lateral sclerosis and locked-in syndrome lead to partial or complete loss of speech, severely restricting communication as voluntary motor control deteriorates. In this study, we developed a non-invasive, ... read more
Aging, the leading risk factor for numerous diseases, manifests through diverse structural and architectural changes in human tissues, providing an opportunity to quantify and interpret tissue-specific aging. To address this, we present a comprehensi... read more
Accurately predicting how amino acid substitutions alter protein function is a central challenge in biology, with applications from interpreting disease variants to engineering vaccines and therapeutic proteins. We introduce HERMES, a family of fast,... read more
Genome-wide association studies have linked millions of genetic variants to biomedical phenotypes, but their utility has been limited by lack of mechanistic understanding and widespread epistatic interactions. Recently, Transformer models have emerge... read more
ObjectiveOur goal was to create open-source software for closed-loop EEG-TMS that allows researchers to rapidly prototype and develop novel stimulation paradigms in a high-level programming language. This addresses the limitations of current solution... read more
Deep visual proteomics (DVP) is an emerging approach for cell type-specific and spatially resolved proteomics. However, its broad adoption has been constrained by the lack of an open-source end-to-end workflow in a community-driven ecosystem. Here, w... read more
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