AI Medical Compendium

Decoding polyphenol-protein interactions with deep learning: From molecular mechanisms to food applications.

Biotechnology advances Jan 14, 2026

Polyphenols and proteins are essential biomolecules that influence food functionality and, by extension, human health. Their interactions-hereafter referred to as PhPIs (Polyphenol-Protein Interactions)- affect key processes such as nutrient bioavail... read more

Artificial intelligence applications in ovarian cancer detection: A systematic literature review of deep learning approaches and clinical translation challenges.

Critical reviews in oncology/hematology Jan 14, 2026

This systematic literature review examines artificial intelligence applications in ovarian cancer detection through analysis of 61 studies published between 2020 and 2025. The investigation reveals advancing methodological sophistication alongside pe... read more

Machine learning based prioritisation of genes associated with osteoarthritis joint damage in animals.

Osteoarthritis and cartilage Jan 14, 2026

OBJECTIVES: To systematically prioritise unstudied genes for their potential to modulate joint damage phenotypes in animal models of osteoarthritis (OA). METHODS: We curated 567 known protein-coding OA-associated genes from the literature and integra... read more

Defining Metrics and the Framework for the Invasive Assessment of Patients with Presumed Coronary Microvascular and Vasomotor Dysfunction.

The Canadian journal of cardiology Jan 14, 2026

The objective of diagnostic investigations should be to confirm or refute the presence of abnormal coronary function and to identify patients who might benefit from specific therapeutic interventions. In the field of coronary microvascular and vasomo... read more

Cutting-Edge AI Technologies in Skin Cancer Applications.

Cancer letters Jan 14, 2026

The rapid development of multimodal large language models (LLMs) such as GPT and Med-PaLM is reshaping medical practice. Skin cancer, one of the most prevalent malignancies, encompasses diverse subtypes and early signs that often resemble benign lesi... read more

Segmentation of the Upper Airway using Deep learning - nnUNet.

Journal of dentistry Jan 14, 2026

OBJECTIVE: This study addresses these challenges by developing a robust and efficient deep learning model for automated segmentation using a large and diverse dataset. The objective of this study is to assess the performance of a deep learning-based ... read more

Machine Learning Predictive Models for Prognosis in Patients undergoing Endovascular Abdominal Aortic Aneurysm Repair.

Annals of vascular surgery Jan 14, 2026

BACKGROUND: An increasing number of patients with abdominal aortic aneurysms (AAAs) are opting for endovascular aneurysm repair (EVAR), and predicting postoperative survival is important for patient management. The development of a postoperative prog... read more

Next-generation lung-cancer-on-a-chip: toward personalized therapy, AI, and CRISPR-driven models.

Drug discovery today Jan 14, 2026

Lung-cancer-on-a-chip (LCOC) technologies have advanced rapidly, yet most models evaluate mechanical strain, patient-derived tumors, multi-organ interactions, artificial intelligence (AI) analytics, and clustered regularly interspaced short palindrom... read more

Intrinsically disordered proteins and liquid-liquid phase separation in drug discovery.

Drug discovery today Jan 14, 2026

Intrinsically disordered proteins (IDPs) and their involvement in liquid-liquid phase separation (LLPS) have reshaped our understanding of how cells organize biochemical reactions in space and time. Unlike structured proteins, IDPs populate highly dy... read more

DMDGRN: A data augmentation-based multilayer directed graph convolutional network for gene regulatory network inference.

Journal of biomedical informatics Jan 14, 2026

OBJECTIVE: Gene regulatory networks (GRNs) provide a graphical representation of the regulatory interactions between transcription factors (TFs) and their target genes, governing transcriptional states that define cell identity and function. Decipher... read more

Artificial Intelligence Medical Compendium