AI Medical Compendium

Digital markers and phenotypes of rest-activity rhythms in people with advanced dementia using real-time location data.

The journals of gerontology. Series A, Biological sciences and medical sciences Jan 14, 2026

BACKGROUND: Disrupted sleep and circadian rhythms in dementia affect rest-activity patterns and impact quality of life, safety, and caregiver burden. The objective of this study is to extend the application of real-time location system (RTLS) technol... read more

CADS: A Causal Inference Framework for Identifying Essential Genes to Enhance Drug Synergy Prediction.

Bioinformatics (Oxford, England) Jan 14, 2026

MOTIVATION: Drug synergy is crucial for developing effective combination therapies, but traditional screening methods suffer from inefficiency and high costs. While deep learning shows promise for predicting drug synergy, current approaches using Tra... read more

Integrating deep-learning methods and web-based data sources for surveillance, forecasting and early warning of avian influenza.

Journal of the Royal Society, Interface Jan 14, 2026

Highly pathogenic avian influenza (HPAI), especially the H5N1 subtype has caused repeated global outbreaks, primarily affecting birds, but occasionally spreading between humans. These events pose serious public health and economic risks, demanding en... read more

Machine learning reveals sequence and methylation determinants of SaCas9-PAM interactions in bacteria.

Nucleic acids research Jan 14, 2026

Cas9 nucleases defend bacteria against invading DNA and can be used with single guide RNAs (sgRNAs) as antimicrobials and genome-editing tools. However, bacterial applications are limited by incomplete knowledge of Cas9-target interactions. Here, we ... read more

Chronic stress raises baseline circulating corticosterone and reduces vocal plasticity in male budgerigars, an avian model for adult vocal learning.

Hormones and behavior Jan 14, 2026

Chronic stress affects cognitive function across many domains, including memory, decision making and learning. While the effects of early-life stress on vocal learning in juveniles are well-demonstrated in both humans and songbirds, less is known abo... read more

Assessment of AI-generated responses to common pregnancy questions: A blinded expert evaluation.

European journal of obstetrics, gynecology, and reproductive biology Jan 14, 2026

INTRODUCTION: We conducted a cross-sectional, blinded expert evaluation of AI-generated answers to 22 frequently asked pregnancy questions to characterize content quality and potential clinical utility. METHODS: Five obstetricians (not involved in ra... read more

DeeBayes: An interpretable deep Bayesian network for ECG signal restoration.

Computers in biology and medicine Jan 14, 2026

The electrocardiogram (ECG) is a valuable and non-invasive tool for detecting and preventing arrhythmias. However, in real-world situations, ECG signals are often contaminated by various types of noise, which can lead to clinical misdiagnoses. As a r... read more

Accurate prediction of anticancer peptides using a stacking ensemble of convolutional and transformer models with conjoint sequence representations.

Computers in biology and medicine Jan 14, 2026

We present a high-performance predictive framework for anticancer peptide (ACP) identification, based on a stacking ensemble learning approach that synergistically combines convolutional neural networks and transformer models using a random forest as... read more

Integrating AI into Dentistry: Technical Pathways and Clinical Applications in Oral Diseases-A Comprehensive Overview.

International dental journal Jan 14, 2026

The application of artificial intelligence (AI) technologies in the management of oral diseases is rapidly increasing, encompassing etiopathogenesis, disease course, diagnosis, treatment plans, and postoperative care. AI demonstrates exceptional perf... read more

Spatial-temporal patterns and drivers of coastal water quality dynamics: Insights from explainable machine learning and PLS-SEM analysis in Xiamen Bay, China.

Marine pollution bulletin Jan 14, 2026

Effective management of coastal water quality is challenging in urbanized regions, where dynamic land-sea interaction and intensifying human pressures drive ecological change. This study proposes an integrated approach that combines Self-Organizing M... read more

Artificial Intelligence Medical Compendium