AI Medical Compendium

Multi-Solvent Graph Neural Network for Reduction Potential Prediction Across the Chemical Space.

Journal of chemical information and modeling Jan 12, 2026

Reduction potentials of redox-active molecules and materials are essential descriptors of their performance as catalysts, antioxidants, electrode materials, etc. For a given species, its practical applications often span a range of solvent environmen... read more

Anatomic subsets of cholangiocarcinoma: More different than alike.

Hepatology (Baltimore, Md.) Jan 12, 2026

Cholangiocarcinoma (CCA) represents a biologically and clinically heterogeneous group of biliary tract malignancies. Growing evidence underscores that the 3 major anatomic subtypes-intrahepatic (iCCA), perihilar (pCCA), and distal (dCCA)-are distinct... read more

Clinical assessment of a Near-Infrared spectroscopy device for rapid triage in traumatic brain injury.

Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia Jan 12, 2026

BACKGROUND: Traumatic Brain Injury (TBI) poses a significant public health challenge in India, with nearly 2 million cases annually and limited CT availability causing delays in diagnosis. This study evaluated CEREBO®, a machine learning-enhanced nea... read more

The potential roles for artificial intelligence in supporting veterinarians during an emergency response.

New Zealand veterinary journal Jan 12, 2026

This article considers how artificial intelligence (AI) could support, within a New Zealand context, the contribution of private veterinarians to protecting animal health and welfare during emergency responses. These may include veterinary involvemen... read more

Benchmarking co-folding methods to predict the structures of covalent protein-ligand complexes.

Acta pharmacologica Sinica Jan 12, 2026

Targeted covalent inhibitors (TCIs) are emerging as a new modality in drug discovery because of their strong binding affinity and prolonged target engagement. However, the rational design of TCIs remains a significant challenge and is hindered by the... read more

Artificial intelligence agents in cancer research and oncology.

Nature reviews. Cancer Jan 12, 2026

Since 2022, artificial intelligence (AI) methods have progressed far beyond their established capabilities of data classification and prediction. Large language models (LLMs) can perform logical reasoning, enabling them to plan and orchestrate comple... read more

Diagnostic Accuracy of Histopathologic Features Suggestive of Dermatophytosis: A Retrospective Cohort Selection Study With Machine Learning Evaluation.

Journal of cutaneous pathology Jan 12, 2026

BACKGROUND: Histopathologic features have been proposed as clues to potential dermatophyte infection. The inter-observer reproducibility and diagnostic accuracy of these features has not been rigorously studied. METHODS: Four blinded assessors at dif... read more

Data-Driven Framework for Determining Site-Specific Attenuation Factors of Arsenic in the Vadose Zone.

Environmental science & technology Jan 12, 2026

Groundwater contamination by arsenic (As) poses a severe health risk to the public. Although the vadose zone plays a crucial role in controlling As transport, current regulatory frameworks conservatively assume an attenuation factor (AF) of 1 for uns... read more

Enhancing CYP450-Ligand Binding Predictions: A Comparative Analysis of Ligand-Based and Hybrid Machine Learning Models.

Journal of chemical information and modeling Jan 12, 2026

Predicting cytochrome P450 (CYP450) ligand binding is critical in early-stage drug discovery as CYP450-mediated metabolism profoundly influences drug efficacy, safety, and adverse reaction risks. However, experimental determination of CYP450-ligand i... read more

Soil microbial diversity, stability, and function are enhanced by cover cropping: A machine learning-based pooled analysis of Mississippi agroecosystems.

The Science of the total environment Jan 12, 2026

Cover cropping has emerged as a pivotal strategy to enhance soil health and microbiome functionality across diverse agroecosystems. However, the extent to which cover crops reshape microbial diversity, composition, functional capacity, and ecological... read more

Artificial Intelligence Medical Compendium