Chronic pain is linked to accelerated brain aging, often measured through the brain-age gap (BAG), the difference between chronological age and neuroimaging-derived brain age. Whether endogenous pain modulation declines with brain aging remains unkno... read more
Journal of esthetic and restorative dentistry : official publication of the American Academy of Esthetic Dentistry ... [et al.]
Jan 6, 2026
BACKGROUND: Artificial intelligence (AI) technologies are increasingly incorporated into restorative and esthetic dentistry; however, their reliability across the complete laminate-veneer workflow remains uncertain. OBJECTIVES: To systematically eval... read more
BACKGROUND: The Ventral Rectopexy International Expert Panel recently published a consensus update on ventral rectopexy. The ability of large language models to synthesize the literature on ventral rectopexy without an explicit knowledge base was stu... read more
This article presents an experimental study of the effects of temperature variations on ultrasonic waves and proposes a methodology to improve the robustness of damage-detection indicators under such environmental conditions. The investigation is bas... read more
OBJECTIVE: To evaluate the utility of a clinical staging model and compared its prognostic performance with an unsupervised machine learning-based stratification method in a real-world cohort of patients with Major Depressive Disorder (MDD). METHODS:... read more
BACKGROUND: Lithium is a core treatment for bipolar disorder (BD), yet clinical response varies across patients. Testing accessible predictors of lithium response is critical for personalization strategies in real-world settings. METHODS: In this cro... read more
Detecting depression from voice recordings is challenging because acoustic indicators are often highly subtle and vary broadly among individuals. A key drawback of current models is their poor cross-lingual generalization; they often degrade sharply ... read more
Cancer cells face a hostile microenvironment characterized by hypoxia, nutrient deprivation, endoplasmic reticulum (ER) stress, and oxidative imbalance. To cope with these challenges, they activate an interconnected network of adaptive pathways inclu... read more
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