Diabetes research and clinical practice
Jan 12, 2026
OBJECTIVE(S): To develop and internally validate an interpretable machine learning model using eXtreme Gradient Boosting (XGBoost) and Shapley Additive exPlanations (SHAP) to predict postpartum glucose intolerance among women with GDM using routine a... read more
OBJECTIVE: We aim to improve Drug-Drug Interactions (DDIs) by explicitly injecting medicinal-chemistry knowledge of functional groups (FGs) into graph neural network (GNN) message passing, in both transductive and inductive settings. Our goal is to (... read more
Epidemiology has long been central to public health, guiding our understanding of the distribution and determinants of disease. As the field has evolved-from John Snow's cholera investigations to large-scale cohort studies and causal inference framew... read more
BACKGROUND: Osteoporosis and sarcopenia are age-related degenerative diseases that frequently co-occur in the older adults, yet their shared molecular mechanisms remain poorly understood. This study aimed to identify common biomarkers. METHODS: By ut... read more
The increasing demand for sustainable food packaging solutions has spurred significant interest in edible films. Marine polysaccharides, as a main source of bioplastics, present a promising alternative to traditional plastic packaging due to their bi... read more
There is an increasing need for fuel flexibility in the conversion of biomass through thermochemical processes such as pyrolysis. Achieving fuel flexibility only through an experimental approach is both expensive and time consuming. Therefore, a numb... read more
Artificial intelligence (AI) is becoming increasingly prevalent in medical practice and has demonstrated sufficient clinical acumen to pass several licensing examinations. We tested the ability of 3 popular large-language models, ChatGPT-4.0 (OpenAI)... read more
The aggregation of nanoparticles (NPs) in aquatic environments is influenced by multiple environmental conditions, with dissolved organic matter (DOM) exerting complex regulatory effects on NPs aggregation. However, traditional models often struggle ... read more
BACKGROUND: Lung adenocarcinoma (LUAD) remains a major clinical challenge in assessment of clinical outcomes and therapeutic response. Although tumor-associated macrophages (TAMs) are known as crucial regulators of tumor progression, their heterogene... read more
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