AI Medical Compendium

AI-assisted predictive monitoring of process control parameters in a novel sequencing batch biofilm reactor for high-strength sewage treatment.

Journal of environmental science and health. Part A, Toxic/hazardous substances & environmental engineering May 31, 2026

This study presents a novel three-zone fibers-based sequencing batch biofilm reactor designed to achieve simultaneous nitrification, denitrification, and phosphorus removal for the treatment of high-strength sewage. Online process control sensors con... read more

σ-p Hyperconjugation-Enabled Covalent Organic Frameworks for Programmable Cascaded Optical Modulation.

Advanced materials (Deerfield Beach, Fla.) May 31, 2026

σ-p hyperconjugation is identified as an effective molecular lever for regulating the excited-state behavior and donor characteristics of covalent organic frameworks (COFs). Activation of σ-p hyperconjugation amplifies the fluorescence quantum yield ... read more

Molecular Engineering of the Nano-Bio Interface for Programmable and Precision Protein Delivery.

Advanced materials (Deerfield Beach, Fla.) May 31, 2026

Protein therapeutics offer unparalleled specificity and immediate bioactivity for addressing complex pathologies; however, their vast therapeutic potential is fundamentally constrained by intrinsic structural vulnerability and the formidable barrier ... read more

Deep Learning Assisted Motion Behavior Analysis of Catalytic Micromotors Based on Trajectory and Optical Flow.

Nano letters May 31, 2026

Investigating micro/nanomotors' (MNMs') motion behavior is crucial for their practical applications and fundamental understanding of propulsion mechanisms. However, existing methods focus exclusively on a single-drive system and lack discriminative c... read more

Mechanistic Insights into PET-MPs-Aggravated Ischemic Stroke via Integrated Computational-Experimental Approaches.

Environmental science & technology May 31, 2026

Microplastics, especially the environmentally pervasive polyethylene terephthalate microplastics (PET-MPs), are important environmental pollutants, and their potential risks to the health of the nervous system are increasingly a concern. Evidence ind... read more

Integrated Network Pharmacology, Molecular Docking, and Experimental Validation for Uncovering the Pharmacodynamic Basis of Sanghuang against Human Pulmonary Fibrosis.

Combinatorial chemistry & high throughput screening May 31, 2026

INTRODUCTION/OBJECTIVE: Sanghuang, a traditional Chinese medicinal fungus, exhibits well-documented anti-inflammatory, antioxidant, and antitumor activities. Emerging preclinical evidence indicates its efficacy in ameliorating bleomycin-induced Pulmo... read more

From unsupervised clustering to atlas-guided annotation in cohort-scale spatial omics with HiCAT

bioRxiv May 31, 2026

Pathologist-annotated tissue regions provide a fundamental reference for examining spatial omics data, yet such annotations are available for a limited number of samples due to the substantial manual effort required. Moreover, these annotations are d... read more

genomics

Instance-Wise Contrastive Graph Neural Network Enables the Discovery of Novel Aedes aegypti Larvicidal Compounds

bioRxiv May 31, 2026

Aedes aegypti remains a major arboviral vector, making larval control a critical strategy to reduce mosquito populations. However, resistance to commercial larvicides has reduced the long-term effectiveness of current interventions, reinforcing the n... read more

bioinformatics

Entropy Fusion DNA: Alignment-Free Gene Fusion Detection through Entropy and Mutual Information Descriptors

bioRxiv May 30, 2026

Gene fusions are clinically relevant genomic alterations and key cancer biomarkers. Their computational detection remains dominated by alignment-based pipelines, whose reliance on read mapping, reference annotations, and heuristic filtering makes the... read more