AI Medical Compendium

Toward equitable digital health: an integrated framework addressing exclusion, ethics, and implementation across healthcare systems.

International journal for equity in health May 29, 2026

BACKGROUND: Digital health technologies are fundamentally reshaping healthcare delivery, access, and governance worldwide. While these innovations offer unprecedented opportunities to extend services, particularly in resource-constrained settings, ea... read more

Why are rural hospitals closing in the U.S.? Predictors identified using explainable machine learning.

BMC health services research May 29, 2026

OBJECTIVE: Rural hospital closures in the U.S. reduce access to essential healthcare services and worsen health and economic outcomes in rural communities. This study uses national longitudinal data and explainable machine learning (XML) to identify ... read more

Explainable machine learning for the prediction of Alzheimer's disease-related cognitive impairment: a consensus feature selection approach.

BMC medical informatics and decision making May 29, 2026

BACKGROUND: Early identification of Alzheimer's disease-related cognitive impairment remains challenging, and existing machine learning (ML) models often suffer from feature instability and limited interpretability. This study developed robust and ex... read more

MSTM-Net: a two-stage prostate cancer segmentation network based on swin-transformer-mamba architecture.

BMC medical imaging May 29, 2026

BACKGROUND: Magnetic resonance imaging (MRI) has become a core imaging modality for prostate cancer screening and diagnosis. Accurate and automatic segmentation of lesion regions is critical for subsequent staging assessment and treatment planning. M... read more

Beyond prediction: explainable machine learning for ferritin estimation from complete blood count.

BMC medical informatics and decision making May 29, 2026

BACKGROUND: Serum ferritin is a primary marker of body iron stores; however, its diagnostic utility is limited by cost and non-specific elevation during inflammatory states. This study aimed to develop and validate explainable machine learning (ML) m... read more

The impact of an artificial intelligence (AI)-assisted education program on mental health, social support and quality of life in older individuals with head and neck cancer: study protocol of a randomized controlled trial.

BMC geriatrics May 29, 2026

BACKGROUND: Head and neck cancer (HNC) is a common malignant tumor, and its treatment often leads to functional impairments in speech, swallowing, and appearance, severely affecting patients' quality of life. Older individuals with HNC, due to the co... read more

A novel prognostic model based on MVIRGs identifies ANGPT2 as a key target driving the malignant progression of HCC.

Biological procedures online May 29, 2026

BACKGROUND: Hepatocellular carcinoma (HCC) is a highly lethal malignancy with high recurrence and limited therapies. Microvascular invasion (MVI) is a critical prognostic factor, but its molecular mechanisms and precise predictive tools are lacking. ... read more

RNA-centric approaches in amyotrophic lateral sclerosis: prospects for future therapeutics.

Expert opinion on therapeutic targets May 29, 2026

INTRODUCTION: Amyotrophic lateral sclerosis (ALS) is a fatal neurodegenerative disorder characterized by profound clinical and molecular heterogeneity, which has substantially hindered the development of effective therapies. Significant advances in A... read more

Clinical governance of artificial intelligence in internal medicine: a literature-informed five-pillar framework for complex care.

Internal and emergency medicine May 29, 2026

Most artificial intelligence (AI) governance frameworks in healthcare address model development, reporting standards, or regulation in broad terms, but do not adequately translate these principles into the operational realities of internal medicine. ... read more

Integrative multi-omics, machine learning, and experimental validation reveal that TPM1 suppresses M2 macrophage polarization and enhances chemosensitivity in acute myeloid leukemia.

Cell biology and toxicology May 29, 2026

BACKGROUND: Acute myeloid leukemia (AML) remains a therapeutic challenge due to chemoresistance and immunosuppression. This study aimed to discover novel regulatory mechanisms in AML pathogenesis. METHODS: Integrative transcriptomic (GSE30029) and pr... read more

Artificial Intelligence Medical Compendium