AI Medical Compendium

Explainable machine learning for estimation of elevated left ventricular filling pressure: a multicenter validation.

Journal of echocardiography May 29, 2026

BACKGROUND: Guideline-recommended algorithms (GL-algorithm) often results in indeterminate left ventricular filling pressure (LVFP). Despite high accuracy, machine learning (ML) methods lack interpretability, which necessitates the development of exp... read more

Validation of an automated AI-based micro-CT organ segmentation workflow against expert annotations and its impact on fluorescence quantification.

European radiology experimental May 29, 2026

OBJECTIVE: Automated, artificial intelligence (AI)-based, organ segmentation has the potential to streamline preclinical imaging workflows, but its suitability must be evaluated not only by geometric accuracy, but also by impact on downstream quantit... read more

Towards an accessible, centralised, searchable database for AI courses in Europe: the Artificial Intelligence in Medical Imaging and Radiation Oncology Education (AIMIROE) project.

European radiology experimental May 29, 2026

OBJECTIVE: Artificial intelligence (AI) is transforming medical imaging and radiation oncology, yet limited understanding and access to education hinder adoption. This study, led by the European Society of Medical Imaging Informatics (EuSoMII) in col... read more

Innovative strategies for early detection of cardiotoxicity: artificial intelligence and multi-modality collaborative models.

Journal of thrombosis and thrombolysis May 29, 2026

Cancer therapeutics account for a significant proportion of new drug development, reflecting advances in diagnosis, treatment, and disease control. However, with this trend comes a responsibility to ensure patient safety both in the near term and ove... read more

M-Tune: imbalanced data handling in machine learning by tuning the decision threshold.

Molecular diversity May 29, 2026

Overprediction of the majority class and poor predictive performance are the major issues when training machine learning classifiers with imbalanced data. This eventually leads to a larger misclassification rate and bias towards the majority class. T... read more

Evaluation of artificial intelligence-based cephalometric analysis compared to the manual method.

Progress in orthodontics May 29, 2026

BACKGROUND: The application of artificial intelligence (AI) to cephalometry has aroused growing interest due to its potential to optimize clinical workflows and improve efficiency. This study aimed to compare the differences and reproducibility of ce... read more

The Role of Multimodal Generative AI in Older Adults' Health Management: Systematic Scoping Review.

JMIR AI May 29, 2026

BACKGROUND: The issue of population aging has emerged as a critical global challenge, driving the imperative for effective self-care and scalable health management solutions for older adults. Against the backdrop of the accelerating application of ge... read more

GraFSyn: An Interpretable Deep Learning Framework for Anticancer Drug Synergy via Graphlet Fingerprints.

Journal of chemical information and modeling May 29, 2026

Predicting drug synergy is important for accelerating the discovery of effective anticancer combination therapies. Synergy intrinsically depends on the precise interactions of key chemical substructures within specific cellular environments. However,... read more

Performance of Large Language Models on the Brazilian National Medical Education Examination: Comparative Benchmark Study.

JMIR medical education May 29, 2026

BACKGROUND: Large language models (LLMs) are rapidly incorporated into medical education and examination preparation; yet, most benchmarking evidence is derived from English-language material. Whether frontier commercial models and Brazilian Portugue... read more

US Food and Drug Administration Shifts to AI-Enhanced Regulatory Review With Elsa 4.0 and HALO.

Journal of medical Internet research May 29, 2026

The US Food and Drug Administration recently announced the launch of Elsa 4.0 and Harmonized AI and Lifecycle Operations for Data (HALO)-an upgrade to its artificial intelligence platform. In this News and Perspectives article, JMIR Correspondent Tej... read more

Artificial Intelligence Medical Compendium