AI Medical Compendium

Topology-Aware Deep Learning on Higher-Order Structures for Drug Response Prediction.

Advanced science (Weinheim, Baden-Wurttemberg, Germany) May 27, 2026

Accurate prediction of anticancer drug response remains a central challenge in precision oncology. Existing approaches often rely on pairwise modeling, overlooking higher-order dependencies among drugs and cell lines. We present TopDr, a topology-awa... read more

Multimodal Artificial Intelligence for Cardiac Amyloidosis Diagnosis: Integrating Echocardiography With Clinical and Laboratory Data for Improved Detection.

Circulation. Cardiovascular imaging May 27, 2026

BACKGROUND: Cardiac amyloidosis (CA) is an underdiagnosed yet treatable cause of heart failure in which timely diagnosis is essential to initiate life-prolonging therapies. While artificial intelligence (AI)-based tools using transthoracic echocardio... read more

An Integrated Machine Learning Workflow Based on Deep Generative Models for Discovery of Inorganic Nonlinear Optical Crystals.

The journal of physical chemistry letters May 27, 2026

The discovery of nonlinear optical (NLO) materials for deep-ultraviolet (DUV) and mid-infrared (MIR) applications remains a significant challenge because of stringent structural and property requirements. While machine learning (ML) has improved the ... read more

Genome-Wide Association Study and Fine Mapping Uncover Key Genetic Loci and Credible Genes of Intracranial Aneurysm and Aneurysmal Subarachnoid Hemorrhage.

Stroke May 27, 2026

BACKGROUND: Intracranial aneurysm (IA) is a common neurovascular disorder; rupture causes aneurysmal subarachnoid hemorrhage with high mortality. Despite available interventions, effective preventative therapies are lacking. We aimed to identify nove... read more

Improving Clinical Efficiency Using Artificial Intelligence Scribe for Documentation (ICE-AID Study): A Retrospective-Prospective Cohort Study at a Quaternary Children's Hospital and Health Service.

Journal of paediatrics and child health May 27, 2026

AIM: To evaluate the impact of an artificial intelligence medical scribe (AIMS) on clinical documentation efficiency, document quality, clinician-patient interaction, clinician well-being, consumer perspectives, overtime, and transcription costs. MET... read more

Dynamic Mechanics and Longitudinal Changes in Temporomandibular Joint Structural Integrity.

Journal of oral rehabilitation May 27, 2026

BACKGROUND: Longitudinal changes in temporomandibular joint (TMJ) structures may reflect joint contact mechanics and jaw loading behaviours (Mechanobehaviour Score, MBS). OBJECTIVE: Test if baseline MBS correlates with longitudinal changes in TMJ str... read more

Prediction of antibody non-specificity using protein language models and biophysical parameters.

mAbs May 27, 2026

The development of therapeutic antibodies requires optimizing target binding affinity and pharmacodynamics, while ensuring high developability potential, including minimizing non-specific binding. In this study, we address this problem by predicting ... read more

Enhancing Molecular Dipole Moment Prediction with Multitask Machine Learning.

The journal of physical chemistry letters May 27, 2026

We present a multitask machine-learning strategy for improving the prediction of molecular dipole moments by simultaneously training on quantum dipole magnitudes and inexpensive Mulliken atomic charges. With dipole magnitudes as the primary target an... read more

AI-assisted case-based learning and flipped classroom to improve clinical decision-making: a randomized controlled trial in reproductive medicine.

Medical education online May 27, 2026

BACKGROUND: Efficient training of reproductive medicine clinicians is critical in the context of declining global fertility and increasing infertility. Traditional lecture‑based instruction often fails to sufficiently develop clinical decision‑making... read more

Targeted screening for heart failure in primary care: evidence, challenges and a pathway-first approach to implementation.

Expert review of cardiovascular therapy May 27, 2026

INTRODUCTION: Heart failure remains a leading cause of morbidity and mortality, yet diagnosis continues to occur late in routine practice, frequently during emergency hospitalization. Primary care is well positioned to detect heart failure earlier, b... read more

Artificial Intelligence Medical Compendium