Differential association of plasma monocyte chemoattractant protein-1 with systemic inflammatory and airway remodeling biomarkers in type-2 diabetic patients with and without asthma.

Journal: Journal of diabetes and metabolic disorders
Published Date:

Abstract

BACKGROUND: Chronic inflammation is a hallmark of type-2 diabetes (T2D) and asthma. Monocyte chemoattractant protein (MCP)-1 or CCL-2 is a key regulator of monocytic infiltration into the sites of inflammation. The changes in systemic MCP-1 levels and its relationship with other inflammatory/immune markers in T2D patients with asthma remain unclear and have been addressed in this study.

Authors

  • Sardar Sindhu
    Immunology & Innovative Cell Therapy Unit, P.O. Box 1180, Dasman, 15462 Kuwait.
  • Merin Koshy
    Immunology & Innovative Cell Therapy Unit, P.O. Box 1180, Dasman, 15462 Kuwait.
  • Areej Abu Al-Roub
    Immunology & Innovative Cell Therapy Unit, P.O. Box 1180, Dasman, 15462 Kuwait.
  • Nadeem Akhter
    Immunology & Innovative Cell Therapy Unit, P.O. Box 1180, Dasman, 15462 Kuwait.
  • Saad Al Zanki
    Immunology & Innovative Cell Therapy Unit, P.O. Box 1180, Dasman, 15462 Kuwait.
  • Shamsha Ali
    Immunology & Innovative Cell Therapy Unit, P.O. Box 1180, Dasman, 15462 Kuwait.
  • Sriraman Devarajan
    Tissue Bank Facility, Dasman Diabetes Institute (DDI), P.O. Box 1180, Dasman, 15462 Kuwait.
  • Rasheed Ahmad
    Immunology & Innovative Cell Therapy Unit, P.O. Box 1180, Dasman, 15462 Kuwait.

Keywords

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