Ginsenoside Rd alleviates mouse acute renal ischemia/reperfusion injury by modulating macrophage phenotype.

Journal: Journal of ginseng research
Published Date: Dec 17, 2015

Abstract

BACKGROUND: Ginsenoside Rd (GSRd), a main component of the root of Panax ginseng, exhibits anti-inflammation functions and decreases infarct size in many injuries and ischemia diseases such as focal cerebral ischemia. M1 Macrophages are regarded as one of the key inflammatory cells having functions for disease progression.

Authors

  • Kaixi Ren
    Department of Infectious Diseases, Tangdu Hospital, The Fourth Military Medical University, Xi'an, China.
  • Chao Jin
    Department of General Surgery, Tangdu Hospital, The Fourth Military Medical University, Xi'an, China.
  • Pengfei Ma
    Department of General Surgery, Xijing Hospital, The Fourth Military Medical University, Xi'an, China.
  • Qinyou Ren
    Department of Traditional Chinese Medicine, Tangdu Hospital, The Fourth Military Medical University, Xi'an, China.
  • Zhansheng Jia
    Department of Infectious Diseases, Tangdu Hospital, The Fourth Military Medical University, Xi'an, China.
  • Daocheng Zhu
    Department of Infectious Diseases, Tangdu Hospital, The Fourth Military Medical University, Xi'an, China.

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