Intramuscular Single-dose Toxicity Test of Bufonis venonum Pharmacopuncture in Sprague-Dawley Rats.

Journal: Journal of pharmacopuncture
Published Date: Dec 1, 2015

Abstract

OBJECTIVES: Bufonis venonum (BV) is the dried white secretions of the auricular and skin glands of the toads Bufo bufo gargarizans or Bufo melanosticus Schneider. This study was performed to evaluate the toxicity of intramuscularly- administered Bufonis venonum pharmacopuncture (BVP) and to calculate its approximate lethality through a single-dose test with Sprague-Dawley (SD) rats.

Authors

  • Kwang-Ho Lee
    Department of Acupuncture & Moxibustion Medicine, College of Korean Medicine, Sangji University, Wonju, Korea.
  • Seung-Ho Sun
    Department of Internal Medicine, College of Korean Medicine, Sangji University, Wonju, Korea.
  • Jun-Sang Yu
    Department of Sasang Constitutional Medicine, College of Korean Medicine, Sangji University, Wonju, Korea.
  • Ki-Rok Kwon
    Research Center of the Korean Pharmacopuncture Institute, Seoul, Korea.

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