Honey Bee Venom (Apis mellifera) Contains Anticoagulation Factors and Increases the Blood-clotting Time.

Journal: Journal of pharmacopuncture
Published Date: Dec 1, 2015

Abstract

OBJECTIVES: Bee venom (BV) is a complex mixture of proteins and contains proteins such as phospholipase and melittin, which have an effect on blood clotting and blood clots. The mechanism of action of honey bee venom (HBV, Apis mellifera) on human plasma proteins and its anti-thrombotic effect were studied. The purpose of this study was to investigate the anti-coagulation effect of BV and its effects on blood coagulation and purification.

Authors

  • Hossein Zolfagharian
    Department of Venomous Animals and Antivenom Production, Razi Vaccine and Serum Research Institute, Karaj, Iran.
  • Mohammad Mohajeri
    Department of Toxicology, School of Pharmacy, Shahreza Branch, Islamic Azad University, Shahreza, Iran.
  • Mahdi Babaie
    Young Researchers and Elites Club, Science and Research Branch, Islamic Azad University, Tehran, Iran.

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