Determination of osimertinib concentration in rat plasma and lung/brain tissues.

Journal: American journal of translational research
Published Date: Dec 15, 2024

Abstract

OBJECTIVES: The aim of this study was to establish an ultra-performance liquid chromatography-tandem mass spectrometry (UPLC-MS/MS) method for the detection of osimertinib in rat plasma, lung and brain tissues.

Authors

  • Yalan Zuo
    Department of Pharmacy, The Fourth Hospital of Hebei Medical University Shijiazhuang 050000, Hebei, China.
  • Peidan Yang
    College of Pharmacy, Hebei Medical University Shijiazhuang 050000, Hebei, China.
  • Ruixia Yang
    Department of Pharmacy, The Fourth Hospital of Hebei Medical University Shijiazhuang 050000, Hebei, China.
  • Juan Hou
    Department of Pharmacy, The Fourth Hospital of Hebei Medical University Shijiazhuang 050000, Hebei, China.
  • Rui Feng
    Department of Pharmacy, The Fourth Hospital of Hebei Medical University Shijiazhuang 050000, Hebei, China.
  • Ping Liang
    Department of Pharmacy, The Fourth Hospital of Hebei Medical University Shijiazhuang 050000, Hebei, China.
  • Jiang Liu
    Department of Pharmacy, The Fourth Hospital of Hebei Medical University Shijiazhuang 050000, Hebei, China.

Keywords

No keywords available for this article.

External Resources

Popular Topics
Recent Journals