Does lower urine-specific gravity predict decline in renal function and hypernatremia in older adults exposed to psychotropic medications? An exploratory analysis.

Journal: Clinical kidney journal
Published Date: Dec 10, 2015

Abstract

BACKGROUND: Exposure to psychotropic agents, including lithium, antipsychotics and antidepressants, has been associated with nephrogenic diabetes insipidus (NDI). This is especially concerning in older adults already at risk of developing chronic kidney disease (CKD) and hypernatremia with advanced aging. This study investigates whether commonly performed random urine-specific gravity (USG) tests can predict adverse NDI outcomes (CKD and hypernatremia) in psychotropic-exposed older adults.

Authors

  • Sahar Sajadi
    Geri-PARTy Research Group, Department of Psychiatry, Jewish General Hospital , McGill University , Montreal, QC , Canada.
  • Ching Yu
    Geri-PARTy Research Group, Department of Psychiatry, Jewish General Hospital , McGill University , Montreal, QC , Canada.
  • Jean-Daniel Sylvestre
    Geri-PARTy Research Group, Department of Psychiatry, Jewish General Hospital , McGill University , Montreal, QC , Canada.
  • Karl J Looper
    Geri-PARTy Research Group, Department of Psychiatry, Jewish General Hospital , McGill University , Montreal, QC , Canada.
  • Marilyn Segal
    Geri-PARTy Research Group, Department of Psychiatry, Jewish General Hospital , McGill University , Montreal, QC , Canada.
  • Soham Rej
    Geri-PARTy Research Group, Department of Psychiatry, Jewish General Hospital, McGill University, Montreal, QC, Canada; Department of Psychiatry, University of Toronto, Toronto, ON, Canada.

Keywords

No keywords available for this article.

External Resources

Popular Topics
Recent Journals