Evaluation of a New Vancomycin Dosing Protocol in Morbidly Obese Patients.

Journal: Hospital pharmacy
Published Date: Oct 14, 2015

Abstract

BACKGROUND: Optimal dosing of vancomycin in morbidly obese patients (>100 kg and at least 140% of their ideal body weight) has not been determined. Conventional dosing strategies have led to the observation of supratherapeutic trough concentrations (>20 mcg/mL).

Authors

  • Desiree E Kosmisky
    Critical Care Pharmacy Specialist, Carolinas Healthcare System , Charlotte, North Carolina.
  • Carrie L Griffiths
    Medical ICU Clinical Pharmacy Specialist, Carolinas Medical Center, Charlotte, North Carolina; Assistant Professor of Pharmacy, Wingate University School of Pharmacy, Wingate, North Carolina.
  • Megan A Templin
    Statistician, Dickson Advanced Analytics Group, Carolinas Healthcare System , Charlotte, North Carolina.
  • James Norton
    Director of Biostatistics, Carolinas Healthcare System, Charlotte , North Carolina.
  • Kelly E Martin
    Infectious Diseases and Antimicrobial Stewardship Clinical Pharmacy Specialist, Carolinas Medical Center, Charlotte , North Carolina .

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