Deep sequencing of HIV-1 variants from paired plasma and cerebrospinal fluid during primary HIV infection.

Journal: Journal of virus eradication
Published Date: Jan 1, 2015

Abstract

BACKGROUND: Limited data exist comparing viral quasispecies between cerebrospinal fluid (CSF) and plasma compartments during primary HIV infection. Deep sequencing is a new method to examine the HIV plasma and CSF quasispecies.

Authors

  • Arjet Gega
    Department of Medicine, School of Medicine, Yale University, New Haven, CT, USA.
  • Michael J Kozal
    Department of Medicine, School of Medicine, Yale University, New Haven, CT, USA.
  • Jennifer Chiarella
    Department of Medicine, School of Medicine, Yale University, New Haven, CT, USA.
  • Evelyn Lee
    Department of Neurology, University of California San Francisco, CA, USA.
  • Julia Peterson
    Department of Neurology, University of California San Francisco, CA, USA.
  • Frederick M Hecht
    Department of Medicine, University of California San Francisco, CA, USA.
  • Teri Liegler
    Department of Medicine, University of California San Francisco, CA, USA.
  • Elizabeth P St John
    454 Life Sciences (a Roche Company), Branford, CT, USA.
  • Birgitte B Simen
    454 Life Sciences (a Roche Company), Branford, CT, USA.
  • Richard W Price
    Department of Neurology, University of California San Francisco, CA, USA.
  • Serena S Spudich
    Department of Neurology, School of Medicine, Yale University, New Haven, CT, USA.

Keywords

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