Evaluation of antiviral activities of Houttuynia cordata Thunb. extract, quercetin, quercetrin and cinanserin on murine coronavirus and dengue virus infection.

Journal: Asian Pacific journal of tropical medicine
Published Date:

Abstract

OBJECTIVE: To evaluate the in vitro activities of the ethyl acetate (EA) fraction of Houttuynia cordata (H. cordata) Thunb. (Saururaceae) and three of its constituent flavonoids (quercetin, quercitrin and rutin) against murine coronavirus and dengue virus (DENV).

Authors

  • K H Chiow
    Department of Microbiology, Yong Loo Lin School of Medicine, National University Health System, National University of Singapore, Kent Ridge, Singapore; Department of Pathology, Yong Loo Lin School of Medicine, National University Health System, National University of Singapore, Kent Ridge, Singapore; Department of Pharmacology, Yong Loo Lin School of Medicine, National University Health System, National University of Singapore, Kent Ridge, Singapore.
  • M C Phoon
    Department of Microbiology, Yong Loo Lin School of Medicine, National University Health System, National University of Singapore, Kent Ridge, Singapore; Department of Pathology, Yong Loo Lin School of Medicine, National University Health System, National University of Singapore, Kent Ridge, Singapore; Department of Pharmacology, Yong Loo Lin School of Medicine, National University Health System, National University of Singapore, Kent Ridge, Singapore.
  • Thomas Putti
    Department of Microbiology, Yong Loo Lin School of Medicine, National University Health System, National University of Singapore, Kent Ridge, Singapore; Department of Pathology, Yong Loo Lin School of Medicine, National University Health System, National University of Singapore, Kent Ridge, Singapore; Department of Pharmacology, Yong Loo Lin School of Medicine, National University Health System, National University of Singapore, Kent Ridge, Singapore.
  • Benny K H Tan
    Department of Microbiology, Yong Loo Lin School of Medicine, National University Health System, National University of Singapore, Kent Ridge, Singapore; Department of Pathology, Yong Loo Lin School of Medicine, National University Health System, National University of Singapore, Kent Ridge, Singapore; Department of Pharmacology, Yong Loo Lin School of Medicine, National University Health System, National University of Singapore, Kent Ridge, Singapore.
  • Vincent T Chow
    Department of Microbiology, Yong Loo Lin School of Medicine, National University Health System, National University of Singapore, Kent Ridge, Singapore; Department of Pathology, Yong Loo Lin School of Medicine, National University Health System, National University of Singapore, Kent Ridge, Singapore; Department of Pharmacology, Yong Loo Lin School of Medicine, National University Health System, National University of Singapore, Kent Ridge, Singapore. Electronic address: micctk@nus.edu.sg.

Keywords

No keywords available for this article.