Population pharmacokinetics and optimization of the dosing regimen of digoxin in adult patients.

Journal: Journal of pharmaceutical health care and sciences
Published Date: Sep 25, 2015

Abstract

BACKGROUND: This study aimed to evaluate the population pharmacokinetics of digoxin in Japanese patients and establish a dosage regimen based on the pharmacokinetic data.

Authors

  • Toshiaki Komatsu
    Department of Pharmacy, Kitasato University Hospital, 1-15-1 Kitasato, Minami-Ku, Sagamihara, Kanagawa 252-0375 Japan.
  • Mami Morita
    Department of Pharmacy, Kitasato University Hospital, 1-15-1 Kitasato, Minami-Ku, Sagamihara, Kanagawa 252-0375 Japan.
  • Futaba Miyaji
    Department of Pharmacy, Kitasato University Hospital, 1-15-1 Kitasato, Minami-Ku, Sagamihara, Kanagawa 252-0375 Japan.
  • Takayuki Inomata
    Department of Cardiovascular Medicine, Kitasato University School of Medicine, Sagamihara, Japan.
  • Junya Ako
    Department of Cardiovascular Medicine, Kitasato University School of Medicine, Sagamihara, Japan.
  • Koichiro Atsuda
    Department of Pharmacy, Kitasato University Hospital, 1-15-1 Kitasato, Minami-Ku, Sagamihara, Kanagawa 252-0375 Japan.

Keywords

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