Serum Lidocaine Levels in Adult Patients Undergoing Cardiac Surgery With del Nido Cardioplegia.

Journal: Annals of thoracic surgery short reports
Published Date: Jan 19, 2024

Abstract

BACKGROUND: Lidocaine in del Nido cardioplegia solution prolongs the refractory period of cardiomyocytes, yielding a longer arrest per dose. Serum lidocaine concentrations >8 mg/L are associated with seizure and cardiotoxicity. We evaluated serum lidocaine concentrations in patients receiving del Nido solution during cardiac surgery.

Authors

  • Danielle I Aronowitz
    Division of Cardiothoracic Surgery, Northwell Health, Manhasset, New York.
  • Karl A Bocchieri
    Division of Cardiothoracic Surgery, Northwell Health, Manhasset, New York.
  • Alan R Hartman
    Division of Cardiothoracic Surgery, Northwell Health, Manhasset, New York.
  • Pey-Jen Yu
    Department of Cardiovascular and Thoracic Surgery, Zucker School of Medicine at Hofstra/Northwell, Manhasset, New York.

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