Fibrinogen Degradation Products and Periodontitis: Deciphering the Connection.
Journal:
Journal of clinical and diagnostic research : JCDR
Published Date:
Dec 1, 2015
Abstract
INTRODUCTION: Fibrinogen degradation products (e.g. D-dimer) arise from digested fibrin clots and fibrinogen. Elevated concentrations accompany activation of coagulation and fibrinolysis and indicate chronic inflammatory diseases. D-Dimer tests are a quick, noninvasive method to rule out abnormal clotting. Periodontitis strongly affects the haemostatic system and evokes a procoagulant state. Correlation of chronic periodontitis with early indicators of disease (biomarkers) might be useful.
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