A new rodent model of cerebral hyperperfusion.

Journal: International journal of clinical and experimental medicine
Published Date: Oct 15, 2015

Abstract

BACKGROUND: Most studies of hyperperfusion and hyperperfusion syndrome after carotid endarterectomy or carotid stenting are based on clinical observation or meta-analyses in patients, whereas there is little corresponding fundamental research since proper animal model that can reproduce phenotype stably is not available. Therefore, we developed a rat model in which the pathophysiologic process of hyperperfusion can be mimicked.

Authors

  • Bin Jia
    Department of Anesthesiology, Xuanwu Hospital, Capital Medical University Beijing, China.
  • Lei Zhao
    Brain Cognition and Brain-Computer Intelligence Integration Group, Kunming University of Science and Technology, Kunming, China.
  • Wei Xiao
    Department of Emergency Medicine, Sir Run Run Shaw Hospital, Zhejiang University School of Medicine, Hangzhou, Zhenjiang Province, China.
  • Bing Cai
    Department of Anesthesiology, Xuanwu Hospital, Capital Medical University Beijing, China.
  • Tian-Long Wang
    Department of Anesthesiology, Xuanwu Hospital, Capital Medical University Beijing, China.
  • Dong-Guo Li
    Biomedical Engineering Institute of Capital Medical University Beijing 100069, China.

Keywords

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