Cell-free supernatant of (RAMULAB51) from coconut inflorescence sap (Neera) enhances glucose uptake and PPAR-γ in 3T3-L1 adipocytes and inhibits α-glucosidase and α-amylase.

Journal: Frontiers in microbiology
Published Date: Dec 23, 2024

Abstract

INTRODUCTION: Lactic acid bacteria are prized for their probiotic benefits and gut health improvements. This study assessed five LAB isolates from Neera, with RAMULAB51 (, GenBank ON171686.1) standing out for its high hydrophobicity, auto-aggregation, antimicrobial activity, and enzyme inhibition. It evaluated RAMULAB51's potential in probiotics and diabetes management, focusing on its effects on digestive enzyme inhibition, glucose uptake, and adipocyte function.

Authors

  • Chandana Kumari V B
    Department of Biotechnology and Bioinformatics, JSS Academy of Higher Education and Research, Mysore, Karnataka, India.
  • Ramith Ramu
    Department of Biotechnology and Bioinformatics, JSS Academy of Higher Education and Research, Mysore, Karnataka, India.
  • Prithvi S Shirahatti
    St. Joseph's College for Women, Rammanahalli, Karnataka, India.
  • Perwez Alam
    Department of Pharmacognosy, College of Pharmacy, King Saud University, Riyadh, Saudi Arabia.
  • Ling Shing Wong
    Faculty of Health and Life Sciences, INTI International University, Nilai, Malaysia.

Keywords

No keywords available for this article.

External Resources

Popular Topics
Recent Journals