Rethinking clinical trials for medical AI with dynamic deployments of adaptive systems.

Journal: NPJ digital medicine
Published Date: May 6, 2025

Abstract

There is a growing recognition of the need for clinical trials to safely and effectively deploy artificial intelligence (AI) in clinical settings. We introduce dynamic deployment as a framework for AI clinical trials tailored for the dynamic nature of large language models, making possible complex medical AI systems which continuously learn and adapt in situ from new data and interactions with users while enabling continuous real-time monitoring and clinical validation.

Authors

  • Jacob T Rosenthal
    Tri-Institutional MD-PhD program of Weill Cornell/Rockefeller/Sloan Kettering, New York, NY, USA. jtr4002@med.cornell.edu.
  • Ashley Beecy
    Division of Cardiology, Department of Medicine, Weill Cornell Medicine and NewYork-Presbyterian, New York, NY, USA.
  • Mert R Sabuncu
    Department of Radiology, Weill Cornell Medicine, New York, NY, USA.

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